Results 71 to 80 of about 270,436 (345)
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Let’s call it a day - The effect of works councils on working hours constraints in german establishments [PDF]
, 2012 This study analyzes the impact of works councils on discrepancies between the preferred and actual working hours of employees. The results show that workers in codetermined establishments are more likely to match their working time preferences.
Gralla, Rafael +2 more
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
The impact of Dutch works councils according to managers [PDF]
Although works councils have, by and large, equally extensive legal rights in Germany and the Netherlands, this is the first econometric analysis that investigates the influence of Dutch works councils on firm performance.
Annette van den Berg +2 more
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Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Works Councils, Quits and Dismissals in Germany [PDF]
, 2013 We examine the relationship between works councils and two different types of employment separation: dismissals by the firm and voluntary quits by employees.
Grund, Christian +1 more
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Revista Crítica de Ciências Sociais, 2007 Based on the experience of Portuguese representatives in European Works Councils (EWC), this text focuses on their evaluation of the fulfillment of the two fundamental principles of the Directive: information and consultation.
Hermes Augusto Costa, Pedro Araújo
doaj +1 more source
The Impact of Works Councils on Wages [PDF]
This paper investigates for the first time the effect of works councils on the anatomy of wages, using matched employer-employee data from the German LIAB for 2001. We find that works councils are associated with higher earnings.
John T. Addison +2 more
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