Results 81 to 90 of about 1,386,615 (307)

SIRT1 Prevents Ferroptosis in Corneal Epithelial Cells by Enhancing HIF1α Protein Stability in Dry Eye Disease

open access: yesAdvanced Science, EarlyView.
Hyperosmotic stress drives ferroptosis in corneal epithelium via SIRT1 downregulation. This work demonstrates that SIRT1 activation stabilizes HIF1α, which transcriptionally upregulates GPX4 to inhibit lipid peroxidation and cell death. The identified SIRT1/HIF1α/GPX4 axis reveals a novel defense mechanism and potential therapy for dry eye disease ...
Lili Lian   +11 more
wiley   +1 more source

4th Congress of the European Project Quality Low Input Food [PDF]

open access: yes, 2008
The fourth annual scientific congress of the QLIF project took place during 19-20 June 2008 at the occassion of the 16th IFOAM Organic World Congress in Modena, Italy, where ISOFAR also organized their 2nd Scientific Conference.
Neuhoff, Daniel
core  

The Faraday Scalpel: Electrochemical Nerve Lesioning Mechanisms Studied in Invertebrate Models

open access: yesAdvanced Science, EarlyView.
Direct‐current produces nerve lesioning through discrete electrochemical reactions. Using hypoxia‐sensitive locust nerves and hypoxia‐tolerant leech nerves, we map three injury pathways: cathodic oxygen reduction, cathodic alkalization, and anodic chloride oxidation. These findings establish electrochemical lesioning—the “Faraday Scalpel”—as a precise,
Petra Ondráčková   +5 more
wiley   +1 more source

Crafts in Shkodra on the Eve of the Ottoman Period (14th – 15th Centuries)

open access: yesKadim, 2021
This paper investigates the development of the main crafts meeting the social needs for food and clothing in the agrarian economy of Shkodra on the eve of the final Ottoman takeover in 1467. It focuces on two archival documents to analyze the development
Ermal Baze
doaj  

Engaging with a history of counselling, spirituality and faith in Scotland: a readers' theatre script [PDF]

open access: yes, 2014
This paper presents an abbreviated version of a verbatim script developed from oral history interviews with individuals key to the development of counselling and psychotherapy in Scotland from 1960 to 2000.
Bondi, Liz   +4 more
core   +3 more sources

Diffusion‐Driven Targeted Passivation of Selenium Vacancies via an I‐Doped CdS Buffer Layer for Efficient Sb2Se3 Solar Cells

open access: yesAdvanced Science, EarlyView.
Iodine incorporation into the CdS buffer layer induces spontaneous anion diffusion and selectively passivates selenium vacancies in Sb2Se3 absorbers. The formation of low‐energy, charge‐neutral ISe defects effectively suppresses non‐radiative recombination, resulting in a substantially enhanced open‐circuit voltage and boosting the device efficiency to
Luyan Shen   +6 more
wiley   +1 more source

IMPROVING THE TEXTILE’S ENTERPRISES KNOWLEDGE MATRIX [PDF]

open access: yesAnnals of the University of Oradea: Fascicle of Textiles, Leatherwork, 2017
The textile enterprises need adequate solutions to face the competition on the global market. Innovation leverages the enterprises competitiveness: however, improving innovation is a task of research providers in the field.
RADULESCU Ion Razvan   +7 more
doaj  

High‐Performance Recycling Biobased Photopolymers for 3D Printing

open access: yesAdvanced Science, EarlyView.
By using biobased phenols like eugenol, novel biobased photopolymers containing dissociative phenol‐carbamate bonds are designed for 3D printing. Meanwhile, a “mixed‐monomer assisted recycling” strategy is proposed to recycle the materials. The resulting materials not only achieve high‐performance and excellent chemical recyclability simultaneously ...
Hang Zhou   +12 more
wiley   +1 more source

Towards an understanding of the social aspects of sustainability in product design: teaching HE students in the UK and Ireland through reflection and peer learning [PDF]

open access: yes, 2014
This paper presents findings from a doctoral study, which investigated effective methods for teaching social sustainability within product design courses in British and Irish universities.
Watkins, M
core   +2 more sources

Hyperlipidemia Aggravates Alveolar Bone Loss via Periodontal Ligament Stem Cell Ferroptosis Through GSK3β Dependent Ubiquitin‐Mediated NRF2 Degradation

open access: yesAdvanced Science, EarlyView.
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang   +11 more
wiley   +1 more source

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