Results 181 to 190 of about 22,933,040 (351)
Improving national alignment to mark 50 years of WHO's essential medicines lists. [PDF]
Moja L, Cappello B, Mubangizi D.
europepmc +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Terrestrial Ecoregions of the World: A New Map of Life on Earth
D. Olson +17 more
semanticscholar +1 more source
A Large and Persistent Carbon Sink in the World’s Forests
Sustainable Forestry +20 more
semanticscholar +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Development of the World Health Organization WHOQOL-BREF Quality of Life Assessment
Professor H. Herrman +32 more
semanticscholar +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Importance of pollinators in changing landscapes for world crops
A. Klein +6 more
semanticscholar +1 more source

