Results 181 to 190 of about 22,933,040 (351)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Prehrana in rak

open access: yesObzornik zdravstvene nege, 1991
World Health
doaj  

Terrestrial Ecoregions of the World: A New Map of Life on Earth

open access: yes, 2001
D. Olson   +17 more
semanticscholar   +1 more source

A Large and Persistent Carbon Sink in the World’s Forests

open access: yesScience, 2011
Sustainable Forestry   +20 more
semanticscholar   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Development of the World Health Organization WHOQOL-BREF Quality of Life Assessment

open access: yesPsychological Medicine, 1998
Professor H. Herrman   +32 more
semanticscholar   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Importance of pollinators in changing landscapes for world crops

open access: yesProceedings of the Royal Society B: Biological Sciences, 2007
A. Klein   +6 more
semanticscholar   +1 more source

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