Results 141 to 150 of about 1,198,222 (315)

News from the Regions: polio will soon be history in the Western Pacific

, 1997
3
World Health Organization
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Global magnitude of visual impairment caused by uncorrected refractive errors in 2004

Bulletin of the World Health Organization, 2008
Estimates of the prevalence of visual impairment caused by uncorrected refractive errors in 2004 have been determined at regional and global levels for people aged 5 years and over from recent published and unpublished surveys.
Serge Resnikoff, Donatella Pascolini, Silvio P Mariotti, Gopal P Pokharel   +3 more
doaj  

Scaling emergency care capacity during concurrent public health and humanitarian crises: outcomes of WHO-ICRC basic emergency care course implementation in the Republic of Moldova

International Journal of Emergency Medicine
Introduction The Republic of Moldova, an upper-middle-income nation in Eastern Europe, has encountered overlapping public health and humanitarian challenges that have tested the resilience of its health system.
Ion Chesov, Jennifer Pigoga Hart, Miljana Grbic, Ion Prisacary, Iuliana Garam, Ihor Perehinets, Emilie J. Calvello Hynes, Dina Pfeifer, Vitalii Stetsyk   +8 more
doaj   +1 more source

Fiebres hemorrágicas víricas : informe de un Comité de Expertos de la OMS [se reunió en Ginebra del 19 al 23 de marzo de 1984]

, 1985
ger In Bundesgesundheitsblatt. - Vol. 29, no. 5 (1986)Russian version of nos. 702-727 bound together (barcode no. 00073791)126 p.A state-of-the-art summary of current laboratory, clinical, and epidemiological findings on 10 viral haemorrhagic fevers, the
World Health Organization, WHO Expert Committee on Viral Haemorrhagic Fevers   +1 more
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Financial report, 1 January--31 December 1970: supplement to the annual report of the Director-General for 1970 and report of the external auditor to the World Health Assembly

, 1971
126 ...
World Health Assembly, 24
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Financial report, 1 January--31 December 1953: supplement to the annual report of the Director-General for 1953 and report of the external auditor to the World Health Assembly

, 1954
77 ...
World Health Assembly, 7
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source