Results 91 to 100 of about 27,130 (265)

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Host perspectives on short-term experiences in global health: a survey

The Lancet Global Health, 2017
Background: Competencies developed for global health education programmes that take place in low-income and middle-income countries have largely reflected the perspectives of educators and organisations in high-income countries.
William Cherniak, MD, Emily Latham, MPH, Barbara Astle, PhD, Geoffrey Anguyo, ChB, Tessa Beaunoir, RN, Joel H Buenaventura, MD, Matthew DeCamp, MD, Karla Diaz, PhD, Quentin Eichbaum, MD, Marius Hedimbi, PhD, Cat Myser, PhD, Charles Nwobu, ChB, Katherine Standish, MD, Jessica Evert, MD   +13 more
doaj   +1 more source

English is must to us: languages and education in Kakuma Refugee Camp, Kenya [PDF]

This thesis explores the interaction between context and attitude in the languagein- education experiences of multilingual refugees in Kakuma Refugee Camp in Northern Kenya, East Africa.
Khasandi-Telewa, Vicky
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Mapping World Anglophone Studies

This book explores core issues in the emerging field of World Anglophone Studies. It shows that traditional frameworks based on the colonial and imperial legacies of English need to be revised and extended to understand the complex adaptations ...

core   +2 more sources

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

Advanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang, Qingfei Meng, Hui Jiao, Huixin Liu, Xiangchao Wang, Honglan Zhou, Yishu Wang   +6 more
wiley   +1 more source

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

Advanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang, Jiajia Liu, Jianguo Wen, Yangyang Luo, Zhiwei Fan, Liren Yang, Xi Hu, Ruihan Luo, Yankai Yu, Sophia Li, Weiling Zhao, Xiaobo Zhou   +11 more
wiley   +1 more source

Africa and Its Diaspora Languages, Literature, and Culture

The text celebrates the academic achievements of Professor Olasope Oyelaran. It brings together over 20 papers by an international group of scholars on African diaspora languages, literatures and culture, representing four generations, all of whom have ...
Sheba, Laide., Oyetade, Akintunde., Orie, Olanike Ola.   +2 more
core  

Information and communication technologies in foreign language learning

, 2010
The adoption of ICT in the school system has far-reaching implications. They include the technical issue of the accommodation of hardware in schools in terms of space, support and costs.
Borthwick, Kate, Dickens, Alison, Corradini, Erika   +2 more
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β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

Advanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He, Jiapeng Bao, Shukang Deng, Weijie Zang, Haoming Yan, Zihao Zhao, Guangze Zhang, Ruiqing Liu, Junjie Chen, Yilin Hu, Wanjiang Xue   +10 more
wiley   +1 more source

Behind classroom codeswitching : culture, curriculum and identity in a Chinese university English department [PDF]

This is an exploratory mixed methods case study which investigates a number of critical issues regarding the teaching and learning of an English Language and Literature Department (henceforth the ELLD) in a Chinese university, including curriculum ...
Zhou, Xiaozhou
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