Results 111 to 120 of about 27,130 (265)

DTX3L Inhibits the EMT, Metastasis, and Stem‐Like Features of Gastric Cancer Through Promoting GSK‐3β Dependent SNAI1 Decay

open access: yesAdvanced Science, EarlyView.
This research identifies DTX3L as a critical tumor suppressor that inhibits epithelial‐mesenchymal transition (EMT), invasion and metastasis in gastric cancer. By functioning as an E3 ubiquitin ligase, DTX3L targets the master EMT regulator SNAI1 for GSK‐3β‐dependent proteasomal degradation.
Yang Chen   +7 more
wiley   +1 more source

Exploited Edens: paradise discourse in colonial and postcolonial literature [PDF]

open access: yes
This thesis examines the relation between figures of paradise and the ideologies and economies of colonialism, imperialism, and global capitalism, arguing that paradise myth is the product of a value-laden discourse related to profit, labour, and ...
Deckard, Sharae Grace
core  

Plurilingualism, Multilingualism, and Lingua Franca English in Today's Globalised World [PDF]

open access: yes
We live in a multilingual world where English serves as the language of international communication. It permeates every sphere of life, from education to trade, from employment to scientific literature.
Cappuzzo, B.
core   +1 more source

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

open access: yesAdvanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu   +8 more
wiley   +1 more source

Humorous and subversive maps in children's literature

open access: yes, 2016
Humorous and subversive maps in children’s books Maps – whether in books for children or adults – fulfill the same basic functions (Sundmark 2014b, Sundmark 2015): they produce a fictional space for the reader, and/or they reference the main events ...
Sundmark, Björn
core  

Modernist Repositionings of Rousseau's Ideal Childhood: Place and Space in English Modernist Children's Literature and Its French Translations [PDF]

open access: yes, 2014
It is a little-known fact that several modernists wrote for children: this project will focus on T.S. Eliot‘s Old Possum‟s Book of Practical Cats, James Joyce‘s The Cat and the Devil, Gertrude Stein‘s The World is Round and Virginia Woolf‘s Nurse Lugton ...
Barai, Aneesh
core  

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

open access: yesAdvanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale   +6 more
wiley   +1 more source

Why won't they learn? : a contrastive study of literature teaching in two Cape Town high school classrooms

open access: yes, 2007
Includes bibliographical references (leaves 71-75).Literature is included as part of most English curricula around the world. South Africa is no exception, and students are expected to study novels, poetry and plays as part of their school language ...
Dyer, Dorothy
core  

Mechanosensitive Piezo1/Osteocalcin/Irisin Axis Protects Against Disuse‐Induced Muscle Atrophy

open access: yesAdvanced Science, EarlyView.
Mechanical unloading suppresses bone Piezo1 expression, which reduces circulating undercarboxylated osteocalcin (unOCN). unOCN reduction subsequently exacerbates IMM‐induced Fndc5/Irisin decrease and drives severe muscle atrophy. Bone Piezo1 activation or exogenous osteocalcin/Irisin ameliorate muscle atrophy, while muscle‐specific Gprc6a or Fndc5 ...
Zhaolu Wang   +5 more
wiley   +1 more source

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