Results 131 to 140 of about 646,830 (303)
Response: An Invitation to a Too-Long Postponed Conversation: Race and Composition by Octavio Pimentel [PDF]
, 2013 Octavio Pimentel’s “Racism and Composition: Redesigning the Composition Classroom to be more Culturally Inclusive” critically provokes pedagogical and programmatic questions by focusing on pressing issues of race and language within a historical context ...
Medina, Cruz
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Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3
Advanced Science, EarlyView.In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang +16 more
wiley +1 more source
Multiple audiences: revisiting historical film reception [PDF]
, 2013 Keynote for the 2013 ECREA Film Studies Conference, Lund, Sweden, 8-9 November ...
Biltereyst, Daniël
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Advanced Science, EarlyView.We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim +6 more
wiley +1 more source
XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss
Advanced Science, EarlyView.Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan +13 more
wiley +1 more source
Destroying the Ethnosphere? How Tourism Has Impacted the Sherpas of Nepal
, 2014 Tourism is perhaps the most salient and impactful process of globalization today. As we are increasingly more mobile, traveling with endless comfort and ease, we explore the far reaches of the planet as ambassadors of our own culture and as agents of ...
Ginder, Joshua H.
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English as common legal language: Its expansion and the effects on civil law and common law lawyers [PDF]
, 2017 English has become the common language in a globalized legal world. However, the far-reaching consequences of the domination of key areas of the international practice of law by legal English are not yet fully understood and analysed.
Künnecke, Martina
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Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium
Advanced Science, EarlyView.This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du +5 more
wiley +1 more source
Advanced Science, EarlyView.Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao +36 more
wiley +1 more source
English Studies as a Site for Healing: A Conversation about Place-Based and Indigenous Pedagogies in the English Classroom [PDF]
, 2017 This article summarizes a roundtable discussion from the 2016 Alaska Native Studies Conference among professors and students from two English Studies courses at the University of Alaska Anchorage: History of the English Language and History of Rhetoric ...
Brook Adams, Heather +5 more
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