Results 111 to 120 of about 6,349,453 (273)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Cutaneous findings following COVID-19 vaccination: review of world literature and own experience. [PDF]

open access: yesJ Eur Acad Dermatol Venereol, 2022
Gambichler T   +8 more
europepmc   +1 more source

Interview with scholar, translator and lexicographer Donald Rayfield [PDF]

open access: yes, 2015
Donald Rayfield is Emeritus Professor of Russian and Georgian at Queen Mary, University of London. He has been at the forefront of Georgian studies for many years and has published widely on Georgia, authoring several major studies on its literature ...
Karetnyk, B, Rayfield, D
core  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Romanticism in world literature Methodical Recommendations for Teaching the Course «Literature in the Context of World Culture» [PDF]

open access: yes, 2011
У статті презентовано методику контекстного вивчення роману Джека Лондона «Мартін Іден» як неоромантичного художнього твору, в якому розкривається проблема трагедії митця-індивідуаліста у суспільстві.Автором представлена методика контекстного изучения ...
Яценко, Таміла Олексіївна
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Trends in the management of anorectal melanoma: A multi-institutional retrospective study and review of the world literature. [PDF]

open access: yesWorld J Gastroenterol, 2021
Bleicher J   +8 more
europepmc   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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