Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The System of Mythological Characters in the Turkic Epic: The Karachay-Balkarian Nartiada and Yakut Olonkho [PDF]
The article explores the parallels in the structure of character systems of the Karachay-Balkarian version of the Nartiada and Yakut heroic epos Olonkho.
Semen S. Makarov, Tanzila M. Khadzhieva
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
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Retracted: Reflections on the Discipline Construction Environment of World Literature and Comparative Literature in the Era of Big Data Analysis. [PDF]
Environmental And Public Health JO.
europepmc +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Flowers of Evil by Charles Baudelaire in the Translations and Edited by N.S. Gumilev (Unfulfilled Project by Publishing House “World Literature”) [PDF]
Based on hitherto unpublished archival documents from the Gorky Archive at IWL RAS and TsGALI, the article analyses the work of Gumilyov as a compiler, translator, and editor of the book Flowers of Evil by Charles Baudelaire, prepared for publication in “
Marina A. Arias-Vikhil +1 more
doaj +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Ivan Kashkin’s Course on American Literary History (1928) [PDF]
The paper is dedicated to Ivan Kashkin’s groundbreaking lecture course on the history of American literature. It lasted several semesters for students of different years, covered literary history of the United States from the 17th century.
Sergey I. Panov, Olga Yu. Panova
doaj +1 more source
Comparing the risk of anaphylaxis requiring epinephrine in oral immunotherapy and subcutaneous immunotherapy: A review of recent Canadian real-world literature. [PDF]
Kovaltchouk U +7 more
europepmc +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source

