Ivan Kashkin’s Course on American Literary History (1928) [PDF]
The paper is dedicated to Ivan Kashkin’s groundbreaking lecture course on the history of American literature. It lasted several semesters for students of different years, covered literary history of the United States from the 17th century.
Sergey I. Panov, Olga Yu. Panova
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Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Retracted: Reflections on the Discipline Construction Environment of World Literature and Comparative Literature in the Era of Big Data Analysis. [PDF]
Environmental And Public Health JO.
europepmc +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
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CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
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Comparing the risk of anaphylaxis requiring epinephrine in oral immunotherapy and subcutaneous immunotherapy: A review of recent Canadian real-world literature. [PDF]
Kovaltchouk U +7 more
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
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The research activities of the Imperial Moscow Archaeological Society founded by count A. S. Uvarov in 1864 were first concentrated mainly in the fields of Russian history, archaeology, traditional culture. The 5th Archaeological Congress held in 1881 in
A. I. Alieva
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Combination therapy in Mucormycosis: Current evidence from the world literature, a mini review. [PDF]
Meena DS, Kumar D, Bohra GK.
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
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