Results 101 to 110 of about 3,618 (265)

Correlative Imaging Platform Linking Taste Cell Function to Molecular Identity

open access: yesAdvanced Science, EarlyView.
A correlative imaging platform is developed to study how individual taste cells respond to different taste qualities. By linking cellular activity with molecular identity and environmental context, dual‐tuned taste cells capable of detecting both sweet and umami stimuli are identified.
Sungho Lee   +6 more
wiley   +1 more source

A história social anglo-americana desde 1945 Anglo-American social history since 1945

open access: yesTempo Social, 2012
O artigo examina temas, métodos e tendências analíticas dominantes na análise da história social e da ciência social produzidas na Inglaterra e nos Estados Unidos a partir da Segunda Guerra Mundial, apontando a proeminência no debate de duas grandes ...
Charles Tilly
doaj  

Development of Endogenous Protein Probes for Characterizing Surface Proteins and Cellular Interactors of Extracellular Vesicles

open access: yesAdvanced Science, EarlyView.
The proximity labeling enzyme APEX2 is displayed on extracellular vesicle (EV) surfaces via genetic fusion with EV‐sorting scaffolds, enabling in situ biotinylation of native surface proteins, adsorbed corona components, and interacting cellular proteins.
Wenyi Zheng   +5 more
wiley   +1 more source

Auto-Paizo Games: Towards Understanding the Design of Games That Aim to Unify a Player’s Physical Body and the Virtual World [PDF]

open access: bronze, 2023
Rakesh Patibanda   +8 more
openalex   +1 more source

Soybean Auxin Transporter PIN3 Regulates Nitrate Acquisition to Improve Nitrogen Use and Seed Traits

open access: yesAdvanced Science, EarlyView.
Xu et al. discovers that switching off auxin transporters in soybean, PIN3a and PIN3b, disrupts auxin flow; this triggers ARF‐STF3/4 signal cascade to activate the nitrate importer NPF2.13 and soil nitrogen acquisition. Multi‐year field trials show edited soybeans maintain yield with higher oil content, offering a potential genetic route to improve ...
Huifang Xu   +16 more
wiley   +1 more source

IMAGINARIOS GLOBALES Y CARTOGRAFÍAS COSMOPOLITAS: LA MODERNIDAD LITERARIA LATINOAMERICANA

open access: yesIntersticios, 2018
El trabajo del crítico literario Mariano Siskind, Deseos cosmopolitas. Modernidad global y literatura mundial en América Latina, se inscribe en el debate por el funcionamiento de las categorías de cosmopolitismo y nacionalismo en el campo literario ...
Mario Federico David Cabrera
doaj  

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

open access: yesAdvanced Science, EarlyView.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su   +15 more
wiley   +1 more source

Learned Conformational Space and Pharmacophore Into Molecular Foundational Model

open access: yesAdvanced Science, EarlyView.
The Ouroboros model introduces two orthogonal modules within a unified framework that independently learn molecular representations and generate chemical structures. This design enables flexible optimization strategies for each module and faithful structure reconstruction without prompts or noise.
Lin Wang   +8 more
wiley   +1 more source

Towards Efficient Auctions in an Auto-bidding World

open access: gold, 2021
Yuan Deng   +3 more
openalex   +1 more source

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