Single‐Droplet Dual‐Target Quantification of circRNA Biomarkers for Colorectal Cancer Screening
Circular RNAs are crucial in tumorigenesis. This study identifies circCK1γ3 and circWDR37 as dual plasma biomarkers for colorectal cancer (CRC) screening. It is developed Casµchip, a droplet microfluidic chip using Cas13a/b technology to quantify these biomarkers.
Jingsong Xu+11 more
wiley +1 more source
[Social determination of health, complexity, coloniality, and the long term]. [PDF]
Sevalho G.
europepmc +1 more source
SGCD presents a novel approach for tissue spatial domain identification by employing interpolation to estimate inter‐spot gene expression and deconvolution to resolve cell‐type composition in both sampled and interstitial regions. By integrating gene expression, cell type, and spatial coordinates within a graph contrastive learning framework, SGCD ...
Tianjiao Zhang+7 more
wiley +1 more source
[What the World Health Organization teaches us about mental health in primary care]. [PDF]
Pérez García MDP+2 more
europepmc +1 more source
Revision of Light-Duty Vehicle Emission Inventories Using Real-World Measurements-Auto/Oil Program, Phase II [PDF]
Alison K. Pollack+7 more
openalex +1 more source
Glioblastoma (GBM) is an aggressive brain cancer that often recurs and resists chemotherapy. This study found that a chemical called PGE2 causes surrounding brain cells (neurons) to become over‐excited, which makes GBM cells resistant to treatment. Researchers developed a new drug, “Compound 11,” which can cross into the brain and effectively block ...
Chih‐Jie Shen+14 more
wiley +1 more source
Brazilian nursing specific situation, middle and micro-range theories: a bibliometric study. [PDF]
Cardoso RB+5 more
europepmc +1 more source
After Lean Production: Evolving Employment Practices in the World Auto Industry edited by Thomas A. KOCHAN, Russell D. LANSBURY and John Paul MACDUFFIE, Ithaca, N.Y.: ILR Press, 1997, 349 p., ISBN 0-8014-8413-8 (pbk. alk. paper), ISBN 0-8014-3382-7 (cloth: alk. paper). [PDF]
Louise Clarke
openalex +1 more source
As an m6A reader, hnRNPA2B1 predominantly regulates specific transcripts (e.g., Ep400, Rrs1) that are essential for chromosome organization and remodeling in an m6A‐dependent manner. Furthermore, it is demonstrated to interact with factors involved in mRNA processing and translation. This dual functionality is pivotal for ensuring the proper occurrence
Lisha Yin+11 more
wiley +1 more source
Social reproduction and health: contributions from Breilh and Lukács to social thinking in collective health. [PDF]
Souza DO.
europepmc +1 more source