Results 21 to 30 of about 3,519 (226)

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Sewell, historia y cultura en un asentamiento humano organizacional. / Sewell, history and culture in organizational human settlement.

open access: yesRevista de Urbanismo, 2003
El texto que sigue a continuación corresponde a una versión abreviada de un trabajo más extenso desarrollado por el autor, con la finalidad de contribuir a efectuar la presentación de Sewell como lugar Patrimonio de la Humanidad ante UNESCO, rescatando y
de Solminihac I., Eugenio
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Dissenting Social Work. Critical Theory, Resistance and Pandemic.

open access: yesPropuestas Críticas en Trabajo Social, 2022
Cursando mi doctorado, hace ya más de 10 años, llegó a mis manos un libro inspirador: Social Work and Social Theory: Making Connections (Policy Press, 2013).
Giannina Muñoz-Arce
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Guerra do Golfo: a crise da nova ordem mundial

open access: yesRevista Brasileira de Política Internacional, 2004
Este artigo, tomando como ponto de partida as Guerras do Golfo, traça o perfil da nova ordem mundial formada com a derrocada da União Soviética e o fim da Guerra Fria, e a ascensão dos Estados Unidos como única superpotência no século XXI. O autor também
Virgílio Caixeta Arraes
doaj   +1 more source

Profound Leadership Strategies: Transcending the Leadership Crisis in the Age of Artificial Intelligence

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article examines the evolving role of organizational leadership amidst the rapid advancements in artificial intelligence (AI). It explores a broadly experienced and documented crisis in leadership, due in part to the disruptive nature of AI and emerging technology.
Rachel Wlodarsky, Davin Carr Chellman
wiley   +1 more source

La microhistoria en la historiografía general

open access: yesHISTOReLo: Revista de Historia Regional y Local, 2009
El texto ofrece una revisión de los estudios locales en el ámbito colombiano. El autor contextualiza el balance con los antecedentes de la historiografía mundial.
Javier Ocampo López
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

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