Results 21 to 30 of about 22,062 (274)

Music Distribution in the Consumer Society: the Creation of Cultural Identities Through Sound [PDF]

open access: yes, 2010
Our behavior is determined by the characteristics of the culture in which we live. Culture imposes on us ways of thinking and perceiving, habits, customs and usages.
Hormigos Ruiz, Jaime   +3 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Entre a crítica, o público e o autor: construção de sentido e crítica social em Brave New World de Aldous Huxley

open access: yesResgate: Revista Interdisciplinar de Cultura, 2015
Esse trabalho tem como principal objetivo discutir o projeto estético criado por Aldous Huxley em seus romances distópicos, especialmente em "Brave New World", primeiramente publicado em 1932. A partir da comparação com alguns outros romances distópicos do mesmo período, pretendemos demonstrar como  parece haver na obra de Huxley um projeto estético ...
openaire   +4 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Некоторые аспекты кодификации феномена современного славянского язычества по данным полевых исследований

open access: yesActa Baltico-Slavica, 2014
Some aspects of the codification phenomenon of contemporary Slavic paganism (in light of from field study material) On the basis of material received from a survey of three Russian pagan associations, the author  discusses some  features of ...
Роман [Roman] Шиженский [Shizhenskiĭ]
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Wiring the labor market

open access: yes, 2000
September ...
David H Autor, Autor, David H.
core   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Sewell, historia y cultura en un asentamiento humano organizacional. / Sewell, history and culture in organizational human settlement.

open access: yesRevista de Urbanismo, 2003
El texto que sigue a continuación corresponde a una versión abreviada de un trabajo más extenso desarrollado por el autor, con la finalidad de contribuir a efectuar la presentación de Sewell como lugar Patrimonio de la Humanidad ante UNESCO, rescatando y
de Solminihac I., Eugenio
doaj   +1 more source

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