Results 111 to 120 of about 177,762,104 (345)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
, 1950 290 p.This volume contains the proposed programme and budget estimates of the World Health Organization for the financial year 1951, as amended after submission to the fifth session of the Executive Board in January ...
World Health Organization
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
International Sanitary Regulations: proceedings of the Special Committee and of the fourth World Health Assembly on WHO Regulations no. 2 [PDF]
, 1952 443 ...
World Health Assembly, 4
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The Little Green Data Book 2017
, 2017 The Little Green Data Book 2017 is based on World Development Indicators 2017 and its online database. Defining, gathering, and disseminating international statistics is a collective effort of many people and organizations.
World Bank
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Fafnir, 2017 This article examines Justin Cronin’s post-apocalyptic novel The Passage (2010), with emphasis on how literal and figurative forms of fragmentation and shifts between temporalities can affect the reader’s storyworld construction.
Maria Lindgren Leavenworth +1 more
doaj
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
, 1990 43 p.This comprehensive index of all issues between 1975 and the end of 1990 replaces and up-dates the World health index 1975-1987 ...
World Health Organization
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