Results 91 to 100 of about 141,531 (307)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
The Small World of Ancient Chinese Characters
, 2007 近幾年來根據1967年Stanley Milgram的想法，D. J. Watts 和 H. S. Strogatz於 1998年所提出的小世界理論已成為一種方法可以用來驗證和對應相對簡單的網路系統下的特定抽象網路種類，例如網際網路、人際關係、神經系統、疾病轉移等等。然而儘管此理論成功地對應複雜系統的關係，此理論不全然能夠成功地預測對於任一擁有獨立(不連結)結點的複雜或簡單的系統，一個解決之道在於處理已知「可信賴性」的問題之上 ...
Lee, Po-Han, 李柏翰
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Studia Humanitatis, 2013 The article deals with the classification of the baroque women’s images in the Danylo Bratkovski’s creation. Based on Baroque antagonism it’s depicted the positive and negative aspects of female nature, their impact on public opinion and public morality
Bai Olena Serhiyivna
doaj
PSYCHOLOGY OF STUDENTS' CHARACTER IN THE WORLD LITERATURE
, 2022 The article depicts the student's character in English literature. The role, genesis, national nature, poetic-typological features and the portrait of students in the works of English literary writers, their character’s features, similarities and differences.
openaire +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
«Speak no more of her»: Silencing the Feminine Voice in Shakespeare’s «Julius Caesar»
ACME, 2016 Although the female characters in Julius Caesar are given little stage time and are ill-treated by their husbands, this article shows that it is not a misogynous play, but a play which effectively depicts a misogynous world. On the one hand, it validates
Natalie Roulon
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source