Results 81 to 90 of about 141,531 (307)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

About the Reader’s “Corporal Compassion” for the Characters of Crime and Punishment [PDF]

open access: yes
The author’s realm of ideas undoubtedly influences the inner life of the reader, but the reader’s somatic involvement in the events of the plot should also be considered.
Elena V. Stepanian
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Writing the War: The Literary Effects of World War One [PDF]

open access: yes, 2006
World War One was a cataclysmic event not only in terms of world history, but also for the literary world. The war’s extreme brutality led to an outpouring of literature concerning its conduct and effects that began with the war poets themselves ...
Wilson, Carolyn RC
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The maximal subgroups of the classical groups in dimension 13, 14 and 15

open access: yes, 2015
One might easily argue that the Classification of Finite Simple Groups is one of the most important theorems of group theory. Given that any finite group can be deconstructed into its simple composition factors, it is of great importance to have a ...
Anna Katharina Schröder   +1 more
core  

Towards Generating Narratives for the Real World

open access: yes, 2018
An immersive, interactive environment and the non-player characters populating it often play a key role in interactive narrative experiences. We posit that if a procedurally generated narrative is better able to reflect real-world attributes of the ...
Azad, Sasha
core   +1 more source

The postmodernism in Serbian literature within the anglophone theories: After the eighties [PDF]

open access: yesZbornik Radova Filozofskog Fakulteta u Prištini
The fiction written by Serbian authors in the eighties and beyond persistently constructs an entirely new world, in which existentialism and metaphysics, myth and literature, literary authors and their projection into literary characters intertwine ...
Gordić-Petković Vladislava S.
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Adaptive methods for on-line recognition of isolated handwritten characters [PDF]

open access: yes, 2002
The main goal of the work presented in this thesis has been the development of an on-line handwriting recognition system which is able to recognize handwritten characters of several different writing styles and is able to improve its performance by ...
Vuori, Vuokko
core  

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