Results 81 to 90 of about 100,721 (259)

Romėnų teatras ir Senekos tragedijos: Pamišęs Herkulis, Edipas. The Roman theatre and Seneca’s tragedies Hercules Furens, Oedipus [PDF]

Literatūra (Vilnius), 2009
The article analyses the feelings of characters in Seneca’s tragedies prior and after recognising their guilt. Expression of the feelings of the characters in Seneca’s two tragedies Hercules Furens and Oedipus is compared, features characteristic of ...
Jovita Dikmonienė
doaj  

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Fragmented Fiction

Fafnir, 2017
This article examines Justin Cronin’s post-apocalyptic novel The Passage (2010), with emphasis on how literal and figurative forms of fragmentation and shifts between temporalities can affect the reader’s storyworld construction.
Maria Lindgren Leavenworth, Van Leavenworth   +1 more
doaj  

Художественная картина мира в романе Лены Элтанг «Каменные клены»| Meninis pasaulėvaizdis Lenos Eltang romane „Akmeniniai klevai“ | Artistic picture of the world in the novel “The stone maples” by Lena Eltang [PDF]

Literatūra (Vilnius), 2013
The article deals with the category of the “artistic picture of the world” and analyzes the way and elements of the personal thinking and world perception of Lena Eltang, which are reflected in her novel “The Stone Maples”.
Galina Mikhailova, Aleksandra Samoylenko
doaj  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Przemiany bohatera w powojennym kinie polskim – od Supermana do Wonder Woman

Postscriptum Polonistyczne, 2020
The article presents the evolution of the heroes in Polish cinema after the Second World War, as well as while showing the characters that influenced the social awareness of Poles, it reveals those which have been created in response to the social needs.
Agnieszka Tambor
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source