Results 81 to 90 of about 1,817,802 (357)

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases

open access: yes
FEBS Letters, EarlyView.
Igor Zivkovic   +2 more
wiley   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

open access: yesFEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker   +8 more
wiley   +1 more source

World trade: pirated by the downturn [PDF]

open access: yes
A post-World War II record decline in world trade is likely in 2009.International trade ...
Cletus C. Coughlin
core  

\u3cem\u3eThe Battle of the Generals: The Untold Story of the Falaise Pocket\u3c/em\u3e by Martin Blumenson [Review] [PDF]

open access: yes, 2012
Review of Martin Blumenson, The Battle of the Generals: The Untold Story of the Falaise Pocket: The Campaign that Should have won World War II.
Dickson, Paul
core   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

open access: yesFEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász   +6 more
wiley   +1 more source

\u3cem\u3eThe Cherry Beret\u3c/em\u3e by Ashton L. Kerr [Review] [PDF]

open access: yes, 2012
Review of Colonel Ashton L. Kerr, MD, The Cherry Beret: Distant recollections of World War II as remembered by one of the first Canloan officers.
Martin, Markus C.
core   +1 more source

Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution

open access: yesFEBS Letters, EarlyView.
The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai   +2 more
wiley   +1 more source

Middle East in World War II

open access: yesVestnik RUDN. International Relations, 2015
The author considers the role and importance of the region of the Middle East and North African theater of operations during World War II, not only the battles occured in the region are analyzed, but also the diplomatic efforts of the allies, related to ...
V I Yurtaev
doaj  

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