Results 151 to 160 of about 1,595,501 (315)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Comparison of the Effect of Ampicillin with Metronidazol plus Gentamicin for Prophylaxis of Wound Infection after Appendectomy in Uncomplicated Appendicitis [PDF]

Introduction : Appendicitis is the most common cause of acute abdominal pain requiring surgical intervention. The infection of a surgical wound is the most common complication in the acute appendicitis, which adds the expenses of drug and cure together ...
شرقی, افشان, واردی, نوشین, پورفرزان, ایرج   +2 more
core  

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Advancements in Smart Wound Dressings: Leveraging Sensor Technology for Real-Time Wound Monitoring and Management. [PDF]

Plast Surg (Oakv)
Sarpong C, Larson JM, Oh I, Devisetti N, Gupta S.   +4 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Fluorescent Light Energy in Feline Surgical and Traumatic Wounds: A Prospective Single-Arm Pilot Study of Healing Progression and Bacterial Findings. [PDF]

Vet Med Sci
Nocera FP, Fantini O, Abate G, Sangiuliano C, Piantedosi D, Marchitelli M, De Martino L, Cortese L.   +7 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Early Experience With Utilizing Biodegradable Temporizing Matrix (BTM) for Complex Pediatric Wound Reconstruction. [PDF]

Plast Surg (Oakv)
Cho SK, Dhanapala Y, Hartley RL, Harrop AR, Fraulin F, Cawthorn TR.   +5 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

How Transformative Are ROS Responsive Hydrogel Nanoformulations to Treat Refractory Infected Wounds. [PDF]

Int J Nanomedicine
Liu Z, Xiang H, Xian K, Cai L, Yin D, Zhong J.   +5 more
europepmc   +1 more source