Results 61 to 70 of about 301,187 (307)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Annular elastolytic giant cell granuloma of conjunctiva: A case report

Indian Journal of Ophthalmology, 2014
Annular elastolytic giant cell granuloma is a condition characterized histologically by damaged elastic fibers associated with preponderance of giant cells along with absence of necrobiosis, lipid, mucin, and pallisading granuloma.
Karabi Konar, Saurabh Sanyal, Arindam Rakshit   +2 more
doaj   +1 more source

Spatial restriction of alpha4 integrin phosphorylation regulates lamellipodial stability and alpha4beta1-dependent cell migration. [PDF]

, 2003
Integrins coordinate spatial signaling events essential for cell polarity and directed migration. Such signals from alpha4 integrins regulate cell migration in development and in leukocyte trafficking.
Ginsberg, Mark H, Goldfinger, Lawrence E, Han, Jaewon, Howe, Alan K, Kiosses, William B   +4 more
core   +1 more source

Pseudo-abelian varieties [PDF]

, 2013
Chevalley's theorem states that every smooth connected algebraic group over a perfect field is an extension of an abelian variety by a smooth connected affine group. That fails when the base field is not perfect.
Totaro, Burt
core   +3 more sources

Oxygen-Sensing Biomaterial Construct for Clinical Monitoring of Wound Healing

Advances in Skin & Wound Care, 2020
ABSTRACT OBJECTIVE Oxygen is essential to wound healing; therefore, accurate monitoring can guide clinical decisions. Clinical wound assessment is often subjective, and tools to monitor wound oxygen are typically expensive, indirect, and highly variable.
Daniel Naveed, Tavakol, Samantha C, Schwager, Lindsay A, Jeffries, Anthony, Bruce, Bruce A, Corliss, Christopher A, DeRosa, Cassandra L, Fraser, Shayn M, Peirce, Patrick S, Cottler   +8 more
openaire   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Implantation of iris-claw Artisan intraocular lens for aphakia in Fuchs′ heterochromic iridocyclitis

Indian Journal of Ophthalmology, 2014
Implantation of iris-claw Artisan intraocular lens (IOL) is a surgical option for correction of aphakia; however, these IOLs have not been used in eyes with uveitis including Fuchs′ heterochromic iridocyclitis (FHI) due to possible risk of severe ...
Ahmad Kheirkhah, Mojgan Nikdel, Hadi Ghadimi   +2 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Intraocular pressure and influencing systemic health parameters in a Korean population

Indian Journal of Ophthalmology, 2014
Aim: To evaluate the relationship between intraocular pressure (IOP) and systemic health parameters such as age, gender, body mass index (BMI), total cholesterol, high density lipoprotein (HDL), and triglyceride (TG) in a Korean population. Materials and
Young Sang Han, Ji Woong Lee, Jong Soo Lee   +2 more
doaj   +1 more source

Status report of the three phase 25 kA, 1.5 kW thermally switched superconducting rectifier, transformer and switches [PDF]

, 1983
A 25 kA, 1.5 kW superconducting rectifier system has been developed. This rectifier system working like an a.c.-d.c, converter with a primary current of 35 A at 0.1Hz, will energize a 25 kA coil with an average power of 5.4 MJ/hr and a proposed energy ...
Holtslag, A.H.M., Kate, H.H.J. ten, Klundert, L.J.M. van de, Knoben, J., Steffens, H.A.   +4 more
core   +2 more sources