Results 71 to 80 of about 891,090 (198)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Characterization of a green-synthesized heteropolysaccharide with promising diabetic wound healing potential

open access: yesResults in Chemistry
Natural polysaccharides are increasingly explored for use in biomaterials, such as wound dressings, due to their excellent biocompatibility, low toxicity, and beneficial biomedical properties.
Imen Trabelsi   +8 more
doaj   +1 more source

Design of wound vegetation restoration measures for upper and lower reservoir connecting road project of pumped storage power station in northwest cold and arid regions [PDF]

open access: yesE3S Web of Conferences
Taking a pumped storage power station in the northwest cold and arid regions as an example, this paper summarizes the construction technology and method of wound vegetation restoration in the upper and lower reservoir connecting road project of pumped ...
Yang Peng   +4 more
doaj   +1 more source

Thyrotropin-releasing hormone (TRH) promotes wound re-epithelialisation in frog and human skin [PDF]

open access: yes, 2013
There remains a critical need for new therapeutics that promote wound healing in patients suffering from chronic skin wounds. This is, in part, due to a shortage of simple, physiologically and clinically relevant test systems for investigating candidate ...
Paredes Roberto   +59 more
core   +2 more sources

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Epigenetic modification: A novel insight into diabetic wound healing

open access: yesHeliyon
Wound healing is an intricate and fine regulatory process. In diabetic patients, advanced glycation end products (AGEs), excessive reactive oxygen species (ROS), biofilm formation, persistent inflammation, and angiogenesis regression contribute to ...
Cong-Cong Ju   +6 more
doaj   +1 more source

L-arginine: A unique amino acid for improving depressed wound immune function following hemorrhage [PDF]

open access: yes, 2002
Objective: To determine whether L-arginine has any salutary effects on wound immune cell function following trauma-hemorrhage. Background. Depressed wound immune function contributes to an increased incidence of wound infections following hemorrhage ...
Hatz, Rudolf A.   +16 more
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Photonic porous silicon as a pH sensor [PDF]

open access: yes, 2014
Chronic wounds do not heal within 3 months, and during the lengthy healing process, the wound is invariably exposed to bacteria, which can colonize the wound bed and form biofilms. This alters the wound metabolism and brings about a change of pH. In this
Zhao, Wei   +14 more
core   +1 more source

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