Results 161 to 170 of about 1,577,605 (357)

IMBALANCES BETWEEN MMPs and TIMPs CONTRIBUTE TO PATHOLOGICAL WOUND HEALING

, 2005
Fibroblasts play a key role in the formation of granulation tissue during wound healing (45). As activated growth factors stimulate fibroblasts from the intact dermis to migrate into the wound bed, MMPs facilitate this migratory process (45,48).

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Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Comprehensive Management of Rhino‐Orbito‐Cerebral Mucormycosis Post‐COVID‐19: A Case Report

Clinical Case Reports
Post‐COVID‐19 mucormycosis, particularly the rhino‐orbital‐cerebral form, can be life‐threatening. This case highlights the importance of maintaining high clinical suspicion, especially in patients with recent COVID‐19 history.
Mohammad Dehbozorgi, Gholamreza Motazedian, Ali Mohammad Fallah‐Tafti, Mehryar Nahaei, Ebtesam Jabari Nia, Fateme Salari, Seyed Ali Nabavizadeh   +6 more
doaj   +1 more source

Travelling waves in wound healing

, 1995
We illustrate the role of travelling waves in wound healing by considering three different cases. Firstly, we review a model for surface wound healing in the cornea and focus on the speed of healing as a function of the application of growth factors ...
Dale, P. D., Olsen, L., Sherratt, J. A., Maini, P. K.   +3 more
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Postoperative Acute Refractory Hypoxemia After Acute Type A Aortic Dissection Surgery: Supporting the Two-Hit Mechanism of Transfusion-Related Acute Lung Injury. A Retrospective Cohort Study

Vascular Health and Risk Management
Mariam Omotolani Afolabi,1 Jiannan Li,1 Jian Wang,2 Mashud Akinfemi Junior Abass,2 AiLing Lin,1 Asta Debora,3 Tinotenda Blessing Madzikatire,4 Jue Wang1 1Department of Cardiac Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou,
Afolabi MO, Li J, Wang J, Abass MAJ, Lin A, Debora A, Madzikatire TB, Wang J   +7 more
doaj  

An audit to determine the clinical effectiveness of a pathway for managing wound infection

, 2015
Prevention of wound infection is a key objective in the planning of care for patients with wounds. The potential for wound infection, particularly in chronic wounds that are heavily contaminated with bacteria, can be high (Bowler et al, 2001).
Stephenson, John, Grothier, Lorraine
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New Encapsulation Technologies for The Development of in Situ Gelling Micro- Nano Particulate Systems for The Wound Healing [PDF]

, 2016
2014 - 2015The Ph.D project titled “New Encapsulation technologies for the development of in situ gelling micro-nano particulate systems for the wound healing” aimed to develop novel topical formulations by innovative technologies, based on supercritical
De Cicco, Felicetta
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