The Importance of Hydration in Wound Healing: Reinvigorating the clinical perspective [PDF]
, 2016 Balancing skin hydration levels is important as any disruption in skin integrity will result in disturbance of the dermal water balance. The discovery that a moist wound healing environment actively supports the healing response when compared to a dry ...
Cutting, K. F. +7 more
core +1 more source
Wound healing and hyper-hydration - a counter intuitive model [PDF]
, 2016 Winters seminal work in the 1960s relating to providing an optimal level of moisture to aid wound healing (granulation and re-epithelialisation) has been the single most effective advance in wound care over many decades.
Cutting, K. F. +4 more
core +1 more source
Augmenting endogenous wnt signaling improves skin wound healing [PDF]
, 2013 Wnt signaling is required for both the development and homeostasis of the skin, yet its contribution to skin wound repair remains controversial. By employing Axin2(LacZ/+) reporter mice we evaluated the spatial and temporal distribution patterns of Wnt ...
Manzano Wilfred R. +57 more
core +1 more source
Tissue transglutaminase in normal and abnormal wound healing: review article [PDF]
, 2004 A complex series of events involving inflammation, cell migration and proliferation, ECM stabilisation and remodelling, neovascularisation and apoptosis are crucial to the tissue response to injury.
Griffin, M +5 more
core +1 more source
Immunohistochemical monitoring of wound healing in antibiotic treated buruli ulcer patients [PDF]
, 2014 While traditionally surgery has dominated the clinical management of Buruli ulcer (BU), the introduction of the combination chemotherapy with oral rifampicin and intramuscular streptomycin greatly improved treatment and reduced recurrence rates.
Arianna Andreoli +9 more
core +1 more source
Delayed wound repair in sepsis is associated with reduced local pro-inflammatory cytokine expression [PDF]
, 2013 Sepsis is one of the main causes for morbidity and mortality in hospitalized patients. Moreover, sepsis associated complications involving impaired wound healing are common.
Marzi, Ingo +15 more
core +1 more source
Wound healing in mice with high-fat diet- or ob gene-induced diabetes-obesity syndromes : a comparative study [PDF]
, 2010 In the past, the genetically diabetic-obese diabetes/diabetes (db/db) and obese/obese (ob/ob) mouse strains were used to investigate mechanisms of diabetes-impaired wound healing.
Stefan Frank +13 more
core +1 more source
Thyrotropin-releasing hormone (TRH) promotes wound re-epithelialisation in frog and human skin [PDF]
, 2013 There remains a critical need for new therapeutics that promote wound healing in patients suffering from chronic skin wounds. This is, in part, due to a shortage of simple, physiologically and clinically relevant test systems for investigating candidate ...
Paredes Roberto +59 more
core +1 more source
Dynamic changes in connexin expression correlate with key events in the wound healing process. [PDF]
, 2003 Wound healing is a complex process requiring communication for the precise co-ordination of different cell types. The role of extracellular communication through growth factors in the wound healing process has been extensively documented, but the role of
Kamaldeep Tamber +9 more
core +1 more source
The role of honey in the management of wounds [PDF]
, 1999 The widespread development of antibiotic-resistant bacteria has generated an increasing interest in the use of alternate therapies for the treatment of infected wounds.
Molan, Peter C.
core +1 more source