Results 51 to 60 of about 1,577,605 (357)

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Recent advances in molecular mechanisms of skin wound healing and its treatments

Frontiers in Immunology
The skin, being a multifaceted organ, performs a pivotal function in the complicated wound-healing procedure, which encompasses the triggering of several cellular entities and signaling cascades.
A. Mamun, Chuxiao Shao, Peiwu Geng, Shuanghua Wang, Jian Xiao   +4 more
semanticscholar   +1 more source

Comparing Self‐Reported and Physician‐Assessed Acne Severity Using Real‐World Data

JEADV Clinical Practice
Background Real‐world data (RWD) offers access to vast amounts of health information; however, limited knowledge exists regarding its reliability in clinical and research practices.
Ali Al‐Mousawi, Somaia Naassan, Misbah Noshela Ghazanfar, Sarah‐Louise Leth Kirsten, Benóný Þór Björnsson, Christian Riemer, Simon Francis Thomsen, Zarqa Ali   +7 more
doaj   +1 more source

Functional Reconstruction of a Combined Tendocutaneous Defect of the Achilles Using a Segmental Rectus Femoris Myofascial Construct: A Viable Alternative

Archives of Plastic Surgery, 2014
The composite anterolateral thigh flap with vascularized fascia lata has emerged as a workhorse at our institution for complex Achilles defects requiring both tendon and soft tissue reconstruction.
Michael Vincent DeFazio, Kevin Dong Han, Karen Kim Evans   +2 more
doaj   +1 more source

Microfibril-associated protein 5 and the regulation of skin scar formation

Scientific Reports, 2023
Many factors regulate scar formation, which yields a modified extracellular matrix (ECM). Among ECM components, microfibril-associated proteins have been minimally explored in the context of skin wound repair.
Chen Han, Trevor R. Leonardo, Bruna Romana-Souza, Junhe Shi, Shalyn Keiser, Heidi Yuan, Mohamad Altakriti, Matthew J. Ranzer, Sammy Ferri-Borgogno, Samuel C. Mok, Timothy J. Koh, Seok Jong Hong, Lin Chen, Luisa A. DiPietro   +13 more
doaj   +1 more source

Delayed wound repair in sepsis is associated with reduced local pro-inflammatory cytokine expression

, 2013
Sepsis is one of the main causes for morbidity and mortality in hospitalized patients. Moreover, sepsis associated complications involving impaired wound healing are common.
Marzi, Ingo, Anna Lena Sander, Heike Jakob, Dirk Henrich, Michael Albig, Roxane Weber, Sommer, Katharina, Weber, Roxane, Jakob, Heike, Sander, Anna Lena, Henrich, Dirk, Ingo Marzi, Albig, Michael, Katharina Sommer, Frank, Johannes, Johannes Frank   +15 more
core   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source

Hydrogel dressings with intrinsic antibiofilm and antioxidative dual functionalities accelerate infected diabetic wound healing

Nature Communications
Dressings for aiding in chronic wound healing can be beneficial, but often involve additional processes or leave residue. Here, the authors report a hydrogel dressing with antibiofilm and antioxidative properties for the treatment of infected diabetic ...
Dicky Pranantyo, C. Yeo, Yang Wu, Chen Fan, Xiaofei Xu, Y. Yip, Marcus Ivan Gerard Vos, Surendra H. Mahadevegowda, Priscilla Lay Keng Lim, Liang Yang, Paula T. Hammond, D. Leavesley, Nguan Soon Tan, M. Chan‐Park   +13 more
semanticscholar   +1 more source

The Role of Oxidative Stress and Antioxidants in Diabetic Wound Healing

Oxidative Medicine and Cellular Longevity, 2021
Foot ulcers are one of the most common and severe complication of diabetes mellitus with significant resultant morbidity and mortality. Multiple factors impair wound healing include skin injury, diabetic neuropathy, ischemia, infection, inadequate ...
L. Deng, Chenzhen Du, Peiyang Song, Tianyi Chen, Shunli Rui, D. Armstrong, Wuquan Deng   +6 more
semanticscholar   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source