Results 51 to 60 of about 895,077 (292)

Characteristics of Serum Exosomes after Burn Injury and Dermal Fibroblast Regulation by Exosomes In Vitro

Cells, 2023
(1) Background: Exosomes (EXOs) have been considered a new target thought to be involved in and treat wound healing. More research is needed to fully understand EXO characteristics and the mechanisms of EXO-mediated wound healing, especially wound ...
Jie Ding, Yingying Pan, Shammy Raj, Lindy Schaffrick, Jolene Wong, Antoinette Nguyen, Sharada Manchikanti, Larry Unsworth, Peter Kwan, Edward Tredget   +9 more
doaj   +1 more source

Safety and Effectiveness of a High‐Dose, Tailored Tissue Plasminogen Activator Therapy Protocol: A Joint Pediatric Hematology and Cardiac ICU Quality Improvement Initiative Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak, Oded Gilad, Yael Feinstein, Sigal Nakav, Ofer Schiller, Joanne Yacobovich   +5 more
wiley   +1 more source

Biomarkers of systemic inflammation are associated with disease severity and metabolic syndrome in patients with hidradenitis suppurativaCapsule Summary

JAAD International
Background: Biomarkers associated with disease severity and comorbid metabolic syndrome (MetS) in patients with hidradenitis suppurativa (HS) are lacking.
Nikolaj Holgersen, MD, Valdemar Wendelboe Nielsen, BSc, Nana Aviaaja Lippert Rosenø, MSc, Jacob P. Thyssen, MD, PhD, Alexander Egeberg, MD, PhD, Signe Holm Nielsen, MSc, PhD, Hans Christian Ring, MD, PhD, Simon Francis Thomsen, MD, PhD   +7 more
doaj   +1 more source

Neuropsychological and Educational Outcomes in Shwachman–Diamond Syndrome—A Report From the North American Shwachman–Diamond Syndrome Registry

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Shwachman–Diamond syndrome (SDS) is a rare autosomal recessive ribosomopathy characterized by bone marrow failure and multisystem involvement, with emerging evidence of associated neurocognitive impairment. Methods We conducted a retrospective study of 240 individuals with biallelic Shwachman–Bodian–Diamond syndrome (SBDS) mutations
Jane Koo, Melissa Gerstle, Leah Cheng, Richard Cooper, Katherine Coyne, Claire Dusa, Naomi E. Joffe, Diana Schwarz, Sarah Steltz, Akiko Shimamura, Kasiani C. Myers, Thea Quinton   +11 more
wiley   +1 more source

The evidence and the rationale for the use of honey as wound dressing [PDF]

, 2011
Although there are now several brands and types of honey wound-care products available as registered medical devices, there is little promotional advertising of honey products for wound care. The misconception that there is no evidence to support the use
Molan, Peter C.
core  

Survival After Hematopoietic Stem Cell Transplantation in Diamond–Blackfan Anemia Syndrome: The Role of Iron Overload—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We assessed the effect of iron overload (IO) on mortality and complications following hematopoietic stem cell transplantation (HSCT) in patients with Diamond–Blackfan anemia syndrome (DBAS) in a systematic review of individual participant data and cohort data from observational studies.
Geoffrey Z. L. Kuppens, Evangelia Kiakou, Lieke de Zwart, Maurizio Miano, Eduard J. van Beers, Marc Bierings, Marije Bartels   +6 more
wiley   +1 more source

Re-introducing honey in the management of wounds and ulcers - theory and practice [PDF]

, 2002
Dressing wounds with honey was standard practice in past times but went out of fashion when antibiotics came into use. There has been a renaissance in its usage now that antibiotic-resistant bacteria have become a widespread clinical problem, and ...
Molan, Peter C.
core  

“PED/PEA-15 regulates wound healing and angiogenesis by affecting cytoskeletal organization and cell motility: a model for diabetic complications” [PDF]

, 2010
Failure in wound healing is a common feature of diabetes mellitus which severely affects morbidity and mortality. We evaluated wound healing in the skin of transgenic mice (TgPED) over-expressing ped/pea-15, a gene over-expressed in patients with type 2 ...
Buonomo, Roberta
core   +1 more source

Skin scarring: Latest update on objective assessment and optimal management

Frontiers in Medicine, 2022
Although skin scarring is considered by some to be a minor, unavoidable consequence in response to skin injury, for many patients, cosmetically unsightly scars may cause uncomfortable symptoms and loss of function plus significant psycho-social distress.
Rubinder Basson, Ardeshir Bayat, Ardeshir Bayat   +2 more
doaj   +1 more source

Fatigue is associated with disease severity in adult patients with hidradenitis suppurativa

JEADV Clinical Practice
Background Patients with hidradenitis suppurativa (HS) experience fatigue, but no studies have yet examined the association between HS severity and fatigue intensity.
Astrid Chodziuk, Nikolaj Holgersen, Valdemar W. Nielsen, Jacob P. Thyssen, Alexander Egeberg, Simon F. Thomsen   +5 more
doaj   +1 more source