Results 81 to 90 of about 1,745,201 (399)
Immunology of Wound Healing [PDF]
Current Dermatology Reports, 2018 Chronic wounds are a tremendous burden on the healthcare system and lead to significant patient morbidity and mortality. Normal cutaneous wound healing occurs through an intricate and delicate interplay between the immune system, keratinocytes, and dermal cells.
Ellis, Samantha +2 more
openaire +5 more sources
Diabetic Wound-Healing Science
Medicina, 2021 Diabetes mellitus is an increasingly prevalent chronic metabolic disease characterized by prolonged hyperglycemia that leads to long-term health consequences.
J. Burgess +4 more
semanticscholar +1 more source
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
Communications Biology, 2021 Jozic et al observe deregulated cytoskeleton components and elevated levels of cortisol and caveolin-1 in chronic wounds. They also show that inducible-keratinocyte specific Cav1 knockout or drug-induced cholesterol disruption in diabetic mice leads to ...
Ivan Jozic +11 more
doaj +1 more source
Healing the Wounds and the Wounds of Healing: A Journey of the Spirit
Journal of Pastoral Care & Counseling: Advancing theory and professional practice through scholarly and reflective publications, 2004 This article is a reflective narrative about the death of a parent told from the perspective of her daughter. It is an experience-based account. This shared journey of mother and child links the familiar realm of the conscious and known self to a realm that is not known in the same way and is not merely the self. It is as if one end is in the midst of
openaire +3 more sources
Angiogenesis in Wound Healing [PDF]
Journal of Investigative Dermatology Symposium Proceedings, 2000 During wound healing, angiogenic capillary sprouts invade the fibrin/fibronectin-rich wound clot and within a few days organize into a microvascular network throughout the granulation tissue. As collagen accumulates in the granulation tissue to produce scar, the density of blood vessels diminishes.
Richard A.F. Clark +2 more
openaire +3 more sources
A fibrocontractive mechanochemical model of dermal wound\ud closure incorporating realistic growth factor kinetics [PDF]
, 2011 Fibroblasts and their activated phenotype, myofibroblasts, are the primary cell types involved in the contraction associated with dermal wound healing.
Hall, C. L. +4 more
core
EUREKA study - The evaluation of real-life use of a biophotonic system in chronic wound management: An interim analysis [PDF]
, 2017 Objective: Interest has grown regarding photobiomodulation (PBM) with low-level light therapy, which has been shown to positively affect the stages of the wound healing process.
Bassetto, Franco +8 more
core +2 more sources
Macrophage polarization in diabetic wound healing
Burns & Trauma, 2022 Impaired wound healing is one of the severe complications of diabetes. Macrophages have been shown to play a vital role in wound healing. In different wound environments, macrophages are classified into two phenotypes: classically activated macrophages ...
Xingqian Wu +6 more
semanticscholar +1 more source
Protein kinase FAM20C—when subcellular localization matters
FEBS Letters, EarlyView.FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley +1 more source