Results 101 to 110 of about 1,577,605 (357)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Therapie chronischer Wunden mit wassergefiltertem Infrarot A (wIRA)

open access: yes, 2008
The central portion of chronic wounds is often hypoxic and relatively hypothermic, representing a deficient energy supply of the tissue, which impedes wound healing or even makes it impossible.
Mercer, James B.   +11 more
core   +2 more sources

Medical honey for wound care—Still the ‘Latest Resort’?

open access: yes, 2008
While the ancient Egyptians and Greeks used honey for wound care, and a broad spectrum of wounds are treated all over the world with natural unprocessed honeys from different sources, Medihoney™ has been one of the first medically certified honeys ...
Santos, Kai   +11 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

A Photothermally Triggered Nanoplatform for Multidimensional Antibacterial Therapy and Accelerated Healing of Infected Wounds

open access: yesInternational Journal of Nanomedicine
Yueying Fan,1,* Jinfu Li,1,* Peng Wang,1,* Yuhuan Peng,1 Chao Yan,1 Xiangyang Li,1 Zhaoxiang Wang,1 Xiao Li,1 Zhanchen He,1 Wenqiang Li,2 Bin Yin,1 Chiyu Jia1 1Center of Burn & Plastic and Wound Healing Surgery, The First ...
Fan Y   +11 more
doaj  

Re-introducing honey in the management of wounds and ulcers - theory and practice

open access: yes, 2002
Dressing wounds with honey was standard practice in past times but went out of fashion when antibiotics came into use. There has been a renaissance in its usage now that antibiotic-resistant bacteria have become a widespread clinical problem, and ...
Molan, Peter C.
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Human adipose-derived stem cell exosomes reduce mitochondrial DNA common deletion through PINK1/Parkin-mediated mitophagy to improve skin photoaging

open access: yesStem Cell Research & Therapy
Backgroud Mitochondrial DNA (mtDNA) deletion and oxidative stress are key contributors to skin photoaging. Mitophagy helps mitigate oxidative stress.
Yihao Wang   +6 more
doaj   +1 more source

In Vitro wound healing effects of single and combined African herbal medicines. [PDF]

open access: yes, 2005
Impaired and aberrant wound healing imposes a huge financial burden in the developed world and is an insurmountable problem in the undeveloped one. Many new approaches, such as gene therapy and tissue engineered skin have met with limited success.
Krishnan, P.R., Krishnan, P R
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

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