Results 101 to 110 of about 483,765 (312)

Atypical Diabetic Foot Ulcer Keratinocyte Protein Signaling Correlates with Impaired Wound Healing

Journal of Diabetes Research, 2016
Diabetes mellitus is associated with chronic diabetic foot ulcers (DFUs) and wound infections often resulting in lower extremity amputations. The protein signaling architecture of the mechanisms responsible for impaired DFU healing has not been ...
Glenn D. Hoke, Corrine Ramos, Nicholas N. Hoke, Mary C. Crossland, Lisa G. Shawler, Joseph V. Boykin   +5 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Heel Pressure Ulcers: a study of wound healing [PDF]

, 2011
Background Heels are a common location for pressure ulcers (PUs); they may be physiologically different to other PU sites and their healing is poorly understood. Aim To summarise the effects of support surfaces and identify prognostic factors in
McGinnis, Elizabeth
core  

Decreased glomerular function is associated with disease severity in patients with hidradenitis suppurativa

Health Science Reports, 2022
Valdemar W. Nielsen, Yiqiu Yao, Jesper G. Holm, Astrid‐Helene R. Jørgensen, Hans C. Ring, Mads Hornum, Simon F. Thomsen   +6 more
doaj   +1 more source

Ultra-Early versus Early Excision and Grafting for Thermal Burns up to 60% Total Body Surface Area; A Historical Cohort Study

Bulletin of Emergency and Trauma, 2016
Objective: To compare the outcome of patients with up to 60% total body surface area (TBSA) thermal burns undergoing ultra-early and early excision and grafting.
Abdolkhalegh Keshavarzi, Mehdi Ayaz, Maryam Dehghankhalili   +2 more
doaj  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

IMBALANCES BETWEEN MMPs and TIMPs CONTRIBUTE TO PATHOLOGICAL WOUND HEALING [PDF]

, 2005
Fibroblasts play a key role in the formation of granulation tissue during wound healing (45). As activated growth factors stimulate fibroblasts from the intact dermis to migrate into the wound bed, MMPs facilitate this migratory process (45,48).

core   +1 more source

Specification and Misconception About COVID-19 Disappearing [PDF]

International Journal of Basic Science in Medicine, 2020
Amir Emami, Fatemeh Javanmardi, Neda Pirbonyeh, Abdolkhalegh Keshavarzi   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Travelling waves in wound healing [PDF]

, 1995
We illustrate the role of travelling waves in wound healing by considering three different cases. Firstly, we review a model for surface wound healing in the cornea and focus on the speed of healing as a function of the application of growth factors ...
Dale, P. D., Olsen, L., Sherratt, J. A., Maini, P. K.   +3 more
core   +1 more source