Results 91 to 100 of about 579,623 (361)

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Experimental phage therapy of burn wound infection : difficult first steps [PDF]

, 2014
Antibiotic resistance has become a major public health problem and the antibiotics pipeline is running dry. Bacteriophages (phages) may offer an ‘innovative’ means of infection treatment, which can be combined or alternated with antibiotic therapy and ...
De Vos, Daniel, Jennes, Serge, Lavigne, Rob, Merabishvili, Maia, Pirnay, Jean Paul, Rose, Thomas, Vaneechoutte, Mario, Verbeken, Gilbert, Zizi, Martin   +8 more
core  

Comprehensive Codified Algorithms to Identify the Underestimated Burden of Hidradenitis Suppurativa in the United States

Dermatology and Therapy
Introduction Hidradenitis suppurativa (HS) is a painful, inflammatory skin disease associated with a high disease burden and long diagnostic delay. Prevalence estimates of HS vary widely in the literature owing to differing estimation methodologies. This
John R. Ingram, Yvonne Geissbühler, John Darcy, Stephen Foley, Alex Gaffney, Aine McConnon, Craig Richardson, Amit Garg   +7 more
doaj   +1 more source

MODERN WOUND DRESSING FOR WOUND INFECTION: AN OVERVIEW

Indonesian Journal of Tropical and Infectious Disease, 2015
When the tissue of skin is break means a wound is happens. To seal it, many choices of wound healing are available. Moist wound dressing can be better optional than the conservative ones.
Novida Rizani
doaj   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Evidence update on prevention of surgical site infection [PDF]

, 2015
Purpose of review: surgical site infection (SSI) is a common health care associated infection and complicates up to 10-20% of operations with considerable health care resources.
Astagneau, Bayat, Blackham, Bonds, Bunn, Cabaluna, Daoud, Darouiche, Edmiston, Fry, Gheorghe, Grauhan, Jakobsson, Kamel, Kent, Kirby, Krieger, Leaper, Leaper, Leaper, Leaper, Leaper, Leaper, Lyytikainen, Matatov, Melling, Pauli, Pinkney, Richet, Sanchez-Manuel, Stannard, Strecker, Tanner, Tanner, Taylor, Thibon, Togioka, Turtiainen, Ubbink, Wang, Webster, Williams, Yokoe   +42 more
core   +1 more source

Modern experimental methods for assessing the effectiveness of tissue-engineered products for hyaline cartilage regeneration

Frontiers in Bioengineering and Biotechnology
Hyaline cartilage (HC) is a specialized connective tissue that covers the surfaces of major joints and is characterized by its limited regenerative capacity.
M. S. Bozhokin, M. S. Bozhokin, Yu. S. Korneva, Yu. S. Korneva, S. A. Bozhkova, E. R. Mikhaylova, D. M. Marchenko, B. R. Rakhimov, B. R. Rakhimov, Y. A. Nashchekina, M. G. Khotin   +10 more
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Comparison of the Effect of Ampicillin with Metronidazol plus Gentamicin for Prophylaxis of Wound Infection after Appendectomy in Uncomplicated Appendicitis [PDF]

Introduction : Appendicitis is the most common cause of acute abdominal pain requiring surgical intervention. The infection of a surgical wound is the most common complication in the acute appendicitis, which adds the expenses of drug and cure together ...
شرقی, افشان, واردی, نوشین, پورفرزان, ایرج   +2 more
core  

Secondary bacterial infections of buruli ulcer lesions before and after chemotherapy with streptomycin and rifampicin [PDF]

, 2013
Buruli ulcer (BU), caused by Mycobacterium ulcerans is a chronic necrotizing skin disease. It usually starts with a subcutaneous nodule or plaque containing large clusters of extracellular acid-fast bacilli.
AA Pahlevan, AB Wysocki, Albert Paintsil, AO Shittu, AO Shittu, AW Bauer, Benjamin Anku, Cynthia Kwakye-Maclean, D Yeboah-Manu, Dorothy Yeboah-Manu, E Coutanceau, E Coutanceau, E Mensah-Quainoo, Evelyn Owusu-Mireku, G Bori, Gerd Pluschke, Grace S. Kpeli, HC Gram, IG Schraibman, Isaac Lamptey, J Guarner, J Hayman, JP Heggers, K GjØdsbØl, K Twum-Danso, KM Dobos, KM George, KM George, Kobina Asan-Ampah, Kwabena Quenin-Fosu, L Katz, M Cruickshank, M Karas, Marie-Thérèse Ruf, MC Robson, Mercy Newman, NA Stotts, NS Levine, Pamela L. C. Small, PG Bowler, RC Daltery, S Adusumilli, S Etuaful, W Curreri, W Majewski, WA Nienhuis   +45 more
core   +3 more sources