Results 71 to 80 of about 572,176 (313)

L-arginine: A unique amino acid for improving depressed wound immune function following hemorrhage [PDF]

, 2002
Objective: To determine whether L-arginine has any salutary effects on wound immune cell function following trauma-hemorrhage. Background. Depressed wound immune function contributes to an increased incidence of wound infections following hemorrhage ...
Angele, Martin K., Angele, Peter, Chaudry, Irshad H., Hatz, Rudolf A., Hernandez-Richter, Thomas, Nitsch, Stefan M., Schildberg, Friedrich Wilhelm, Wichmann, Mathias W.   +7 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Comparison of Injury Severity Score (ISS) and New Injury Severity Score (NISS) in the Evaluation of Thoracic Trauma Patients: A Retrospective Cohort Study

Emergency Medicine International
Objective. To explore the value of the injury severity score (ISS) and the new injury severity score (NISS) for evaluating injuries and predicting complications (pneumonia and respiratory failure) and poor prognoses (in-hospital tracheal intubation ...
He Jin, Yuanyuan Zhang, Qi Zhang, Lijuan Ouyang, Xueyao Li, Yiyan Zhang, Baosheng Yang, Junfeng Sun, Chaohui Wei, Guimei Yang, Li Guan, Shilan Luo, Junyu Zhu, Huaping Liang   +13 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Hidradenitis Suppurativa Symptom Daily Diary (HSSDD) and Questionnaire (HSSQ): Psychometric Validation and Interpretation Threshold Derivation Using Phase 3 Study Data

Dermatology and Therapy
Introduction Hidradenitis suppurativa (HS) is a chronic inflammatory disease characterised by painful skin lesions which negatively impact patients’ physical and mental wellbeing. The HS Symptom Daily Diary (HSSDD) and HS Symptom Questionnaire (HSSQ) are
John R. Ingram, Jérémy Lambert, Valerie Ciaravino, Robert Rolleri, Ingrid Pansar, Luke Peterson, Christopher G. Pelligra, Linnea Thorlacius   +7 more
doaj   +1 more source

Interpretation of wound infection risk assessment, identification and diagnosis in "Wound infection in clinical practice：principles of best practice（2022 edition）" by the International Wound Infection Institute

Huli yanjiu, 2023
This paper interpreted the contents of wound infection risk assessment，infection identification and diagnosis in "Wound infection in clinical practice：principles of best practice（2022 edition）" by the International Wound Infection Institute，in order to ...
ZHENG Hongling, JIANG Lu, SU Qiong
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Research on Strategies for Wound Healing and Infection Control in Skin Disease Nursing [PDF]

SHS Web of Conferences
The skin, as the largest organ in the human body, plays multiple roles such as protecting, sensing, and regulating body temperature. Wound healing and infection control are two extremely important links, in the treatment and care of skin diseases ...
Yang Xiaoyu
doaj   +1 more source

Application of Wound Closure Molndal Technique after Laparoscopic Cholecystectomy – Initial Comparative Study [PDF]

, 2010
Because of a possible delayed wound healing, critical colonization and infection of wounds present a problem for surgeons1–3. Colonized and infected wounds are a potential source for cross-infection1–3.
Igor Medved, Iva Juretić, Juraj Ahel, Marin Marinović, Nikola Gržalja, Tedi Cicvarić   +5 more
core   +1 more source

Hydrogen Peroxide Wound Irrigation in Orthopaedic Surgery. [PDF]

, 2017
As the burden of deep hardware infections continues to rise in orthopaedics, there is increasing interest in strategies for more effective debridement of colonized tissues and biofilm.
Hansen, Erik Nathan, Lu, Min
core   +1 more source