Results 61 to 70 of about 413,850 (218)

Effect of polydeoxyribonucleotide therapy on the regeneration of long-term non-healing postoperative skin defects

RUDN Journal of Medicine
Relevance. Chronic wound healing currently remains a serious problem due to its frequency and associated complications. Polydeoxyribonucleotide therapy, which promotes angiogenesis and tissue regeneration, offers a promising treatment.
Alexey G. Baranovskiy, Yelena Yu. Shapovalova, Yuri G. Baranovskiy, Boris I. Kuzminov, Svetlana V. Harchenko, Igor A. Lugin, Lilian A. Kutuzova, Tatiana P. Sataieva, Sergey V. Popov, Kamil R. Bakhtiyarov, Daniil Yu. Yuferov, Grigory A. Demyashkin   +11 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Clinical efficacy of ultrasound debridement in the treatment of purulent wounds

Вестник хирургии имени И.И. Грекова
The OBJECTIVE was to study the clinical course of purulent wounds with topical application of ultrasound treatment.METHODS and MATERIALS. The study involved 70 patients undergoing inpatient treatment in the department of purulent surgery in the period ...
E. L. Stavchikov, S. D. Fedianin, I. V. Zinovkin, A. V. Marochkov   +3 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

The Effect of Tissue-Engineered Wound Dressing Comprising Copper, on the Healing Process of Full-Thickness Wound in Mouse Model

مجله دانشکده پزشکی اصفهان, 2018
Background: Production of skin dressings or substitutes is one of the most important tissue engineering fields. Since copper is an important agent in skin extracellular matrix synthesis, we investigated the effect of collagen-gelatin-bioglass scaffolds ...
Akram Alizadeh, Samiramis Pourmotabed, Golnaz Khorasanizadeh, Maryam Anjomshoa, Esmaeel Sharifi   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

MODERN ASSORTMENT, PROPERTIES AND PERSPECTIVES OF MEDICAL DRESSINGS IMPROVEMENT OF WOUND TREATMENT

Фармация и фармакология (Пятигорск), 2018
The effectiveness of reparation is now characterized not only in terms of wound healing. The aesthetic result is also of great significance. Besides, it is important to ensure the comfort of medication, in order to combine the optimal therapy and the ...
A. V. Mayorova, B. B. Syisuev, I. A. Hanalieva, I. V. Vihrova   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source