Results 121 to 130 of about 390,386 (244)

Exploring the Impact of Urolithins A and B on Muscle Health: A Transcriptomic Analysis in Human Myotubes

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Urolithin A (UA) and urolithin B (UB) are gut microbiota‐derived metabolites of ellagitannins reported to influence mitochondrial function, inflammation and muscle metabolism. Their comparative transcriptomic effects in human skeletal muscle cells remain undefined.
Yves Henrotin, Antoine Florin, Christelle Sanchez, Prescilia Centonze, Tiago Pinto Coelho, Sophie Bekisz, Jean‐Emile Dubuc, Olivier Galand, Cécile Lambert   +8 more
wiley   +1 more source

Extracellular Vesicle‐Bound Bacterial Toxin Pneumolysin Triggers Membrane Engagement and Damage Beyond Canonical Pore Formation

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
Bacterial toxin hijacks host microvesicles to breach cell membranes Microvesicles derived from challenged host cells carrying the pneumococcal pore‐forming toxin pneumolysin promote fusion with target cells and membrane permeabilisation. Our integrated experimental and computational study reveals a mechanism by which PLY‐lipid interactions enable ...
Aswathy C. Sagilkumar, Avinashi Lal Kushwaha, Anushka Shitut, Dheeraj Kumar Sarkar, Sruthika Sukumar, Subhajit Mahanty, Somnath Dutta, Jagannath Mondal, Karthik Subramanian   +8 more
wiley   +1 more source

Osmotic Remodeling of Extracellular Vesicles for Precision Nanomedicine

Small, Volume 22, Issue 56, 8 October 2026.
Hypotonic lysis in bidistilled water is used to remodel B lymphocyte–derived extracellular vesicles into cargo‐depleted, structurally preserved nanovesicles. The process reduces intraluminal proteins and nucleic acids, reshapes membrane composition, and enhances tumor‐cell uptake in vitro, while allowing proof‐of‐concept reloading with exogenous agents,
Francesca Susa, Lorenzo Arnaboldi, Veronica De Giorgis, Marco Ghirimoldi, Elettra Barberis, Marco Brucale, Francesco Valle, Mario Malerba, Marta Vallino, Angelo Musicò, Roberto Frigerio, Alessandro Gori, Vera Mugoni, Claudia Voena, Roberto Pisano, Fabrizio Pirri, Silvia Arpicco, Marcello Manfredi, Tania Limongi   +18 more
wiley   +1 more source

Oleic Acid‐Mediated Double Emulsification Enables Enhanced Aqueous Stability and Localized Photothermal Heating of Liquid Metal Droplets

Small Methods, Volume 10, Issue 19, 7 October 2026.
Oleic acid‐mediated double emulsification creates a yolk–shell‐like liquid metal photothermal platform in which the intermediate oil phase limits water transport to the liquid metal and reduces convection‐mediated heat dissipation from the irradiated region.
Eunju Na, Youngwon Kim, Jihye Kim, Sang Kug Chung, Yongmin Cho, Bongseop Kwak, Joohyung Lee   +6 more
wiley   +1 more source

Design of a high-efficiency brushless wound rotor synchronous machine with reduced torque ripple employing a novel stator winding scheme. [PDF]

PLoS One
Ul Haq MA, Farooq H, Liaqat R, Khan ZA, Altamimi A.   +4 more
europepmc   +1 more source

Clear‐Air Turbulence Upstream of a Hydraulic Jump Leading to a Helicopter Accident—A Large Eddy Simulation

Earth and Space Science, Volume 13, Issue 10, October 2026.
Abstract This study investigates clear‐air turbulence that triggered a helicopter accident in the lee of a mountain range near Koriyama, Japan, on 1 February 2020. Using numerical weather prediction models with horizontal resolutions of 1 km and 100 m, we examined the environmental conditions and mechanisms responsible for the turbulence.
J. Ito, H. Niino, K. Saito, K. Okuyama
wiley   +1 more source

Molecular Engineering Boosts Photon‐Activated Immunotherapy for Prostate Cancer Through Concurrent Pyroptosis and cGAS‐STING Pathway Activation

Angewandte Chemie, Volume 138, Issue 39, 21 September 2026.
The engineered DTSe‐based photosensitizer, DZTSe, emerges as an avant‐garde molecular entity, which can distribute to both the endoplasmic reticulum and mitochondria to concurrently trigger pyroptosis and activate the cGAS‐STING pathway. This dual‐action strategy effectively reprograms the tumor microenvironment, enabling potent eradication of primary ...
Cheng Zhang, Xiaolan Yin, Jeongyeon Hong, Qixian Chen, Weijie Chi, Jingyun Wang, Juyoung Yoon, Haidong Li   +7 more
wiley   +2 more sources

A novel self excited hybrid brushless wound rotor synchronous machine with consequent poles. [PDF]

Sci Rep
Ul Haq MA, Farooq H, Liaqat R, Khan ZA, Altamimi A.   +4 more
europepmc   +1 more source

Dapagliflozin Attenuates NKCC2 Protein Expression and Alleviates Diabetic Kidney Disease in Salt Loaded‐Hypertensive Diabetic Db/Db Mice

FASEB BioAdvances, Volume 8, Issue 10, October 2026.
In salt‐loaded, hypertensive diabetic db/db mice with diabetic kidney disease, dapagliflozin lowered blood pressure and reduced tubular and glomerular injury. Mechanistically, dapagliflozin increased cullin E3 ligase abundance, promoting degradation of NKCC2.
Zenab Shahzad, Niharika Bala, Arooba Illyas, Amir Kazory, Indra Chandrasekar, Abdel A. Alli   +5 more
wiley   +1 more source

A novel rotor harmonic winding-based high efficient self-excited brushless wound rotor synchronous machine with improved torque features. [PDF]

Sci Rep
Ul Haq MA, Farooq H, Liaqat R, Khan ZA, Altamimi A.   +4 more
europepmc   +1 more source