Results 51 to 60 of about 31,354 (292)

Generic composite flywheel designs [PDF]

open access: yes, 1984
Fiber reinforced composites belong to a new class of materials and allow great flexibility in flywheel design. The most efficient flywheel may no longer have the classic Stodola taper and indeed, may not even be round.
Steele, R. S.
core   +1 more source

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

open access: yesAdvanced Science, EarlyView.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du   +5 more
wiley   +1 more source

Review of centrifugal liquid-liquid chromatography using aqueous two-phase solvent (ATPS) systems: Its scale-up and prospects for the future production of high-value biologics [PDF]

open access: yes, 2007
The future challenges in bioprocessing include developing new downstream processes for the purification and manufacture of the protein based medicines of the future to relieve the predicted bottleneck being produced by increasingly high titres from ...
Sutherland, I A
core  

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

open access: yesAdvanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong   +12 more
wiley   +1 more source

Design and Optimization of a Novel Wound Field Synchronous Machine for Torque Performance Enhancement

open access: yesEnergies, 2018
This paper presents the design and optimization of a novel wound field synchronous machine topology, in which permanent magnets (PMs) are introduced into the rotor slot opening with segment configuration for high quality output torque performance.
Wenping Chai   +2 more
doaj   +1 more source

Preliminary design and optimization of toroidally-wound limited angle servo motor based on a generalized magnetic circuit model [PDF]

open access: yes, 2016
This paper proposes a new generalized equivalent magnetic circuit model for the preliminary design of a toroidally-wound limited angle servo motor (LASM).
Jiao, Zongxia   +4 more
core   +1 more source

Alkaline Phosphatase‐Activated NIR‐II AIEgens Nanosystem for Surgical and Postoperative Closed‐Loop Therapy of Advanced Osteosarcoma

open access: yesAdvanced Science, EarlyView.
This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu   +14 more
wiley   +1 more source

AXL Promotes Ischemic Myelin Repair Through Alleviating Myelin Debris Deposition and Lipid Droplets Accumulation

open access: yesAdvanced Science, EarlyView.
Microglial AXL drives white matter repair after stroke by orchestrating the cleanup of myelin debris. Mechanistically, AXL signals through EGR1 to boost Smpd1 transcription, regulating sphingolipid metabolism and preventing lipid droplet toxicity. Restoring the pathway with ASM therapy mitigates damage, positioning AXL as a key node for therapeutic ...
Junqiu Jia   +13 more
wiley   +1 more source

Visualizing and Quantifying Impact with Mechanochromic Sensing Paints Based on Self‐Assembled Polydiacetylene‐Silk Core‐Shell Vesicles

open access: yesAdvanced Science, EarlyView.
Tracking physical impacts is important in many fields. Self‐assembled microparticles made from polydiacetylene and silk fibroin that change color from blue to red when hit can provide an alternative approach to traditional mechanical transducers, quantitatively visualizing impact with responses ranging from <100 to 770 N.
Marco Lo Presti   +4 more
wiley   +1 more source

Hybrid Brushless Wound-Rotor Synchronous Machine with Dual-Mode Operation for Washing Machine Applications

open access: yesMachines
This paper proposes a hybrid brushless wound-rotor synchronous machine (HB-WRSM) with an outer rotor topology that can operate as a permanent magnet synchronous machine (PMSM), as well as an HB-WRSM.
Sheeraz Ahmed   +4 more
doaj   +1 more source

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