Results 81 to 90 of about 136,977 (289)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Stress-Triggered Long-Distance Communication Leads to Phenotypic Plasticity: The Case of the Early Root Protoxylem Maturation Induced by Leaf Wounding in Arabidopsis

Plants, 2018
Root architecture and xylem phenotypic plasticity influence crop productivity by affecting water and nutrient uptake, especially under those environmental stress, which limit water supply or imply excessive water losses.
Ilaria Fraudentali, Renato Alberto Rodrigues-Pousada, Alessandro Volpini, Paraskevi Tavladoraki, Riccardo Angelini, Alessandra Cona   +5 more
doaj   +1 more source

Alignment between PIN1 Polarity and Microtubule Orientation in the Shoot Apical Meristem Reveals a Tight Coupling between Morphogenesis and Auxin Transport [PDF]

, 2010
Morphogenesis during multicellular development is regulated by intercellular signaling molecules as well as by the mechanical properties of individual cells.
A Peaucelle, A. C Newell, A. J Fleming, A. R Paredez, A. R Paredez, C Lloyd, Carolyn Ohno, D Reinhardt, D Reinhardt, D. D Fisher, E. J Chapman, E. M Bayer, Elliot M. Meyerowitz, F Corson, F. A Ditengou, G. J Mitchison, G. V Reddy, H Jonsson, Henrik Jönsson, J Craft, J Friml, J Marc, J Petrasek, J. A Raven, Jan Traas, K Okada, M. G Heisler, Magalie Uyttewaal, Marcus G. Heisler, N Geldner, N. C Shaner, O Grandjean, O Hamant, Olivier Hamant, Ottoline Leyser, P Sahlin, P. B de Reuille, P. H Rubery, Pawel Krupinski, R Gutierrez, R Himmelspach, R. E Peterson, R. E Williamson, R. S Smith, S Douady, S Sakaguchi, W. R Scheible, Y Boutte, Y Cheng   +48 more
core   +6 more sources

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Characterizing the Palm Pathogenic Thielaviopsis Species from Florida

Journal of Fungi
Thielaviopsis paradoxa sensu lato is a soilborne fungal pathogen that causes Thielaviopsis trunk rot and heart rot in palms. The loss of structural integrity resulting from trunk rot can cause the palm trunk to collapse suddenly and poses a serious ...
Marie-Gabrielle Ayika, Avril Rosano, Jacqueline Valiente, Seemanti Chakrabarti, Jeffrey A. Rollins, Braham Dhillon   +5 more
doaj   +1 more source

NHL25 and NHL3, Two NDR1/HIN1-Like Genes in Arabidopsis thaliana with Potential Role(s) in Plant Defense

Molecular Plant-Microbe Interactions, 2002
The Arabidopsis genome contains 28 genes with sequence homology to the Arabidopsis NDR1 gene and the tobacco HIN1 gene. Expression analysis of eight of these genes identified two (NHL25 and NHL3 for NDR1/HIN1-like) that show pathogen-dependent mRNA ...
Anne Varet, Jane Parker, Pablo Tornero, Norbert Nass, Thorsten Nürnberger, Jeffery L. Dangl, Dierk Scheel, Justin Lee   +7 more
doaj   +1 more source

New Onset of Fibromyalgia After Exposure to a Combat Environment: A Longitudinal Cohort Study

Arthritis Care &Research, EarlyView.
Objective Traumatic life events are hypothesized to be triggers for the onset of fibromyalgia. Posttraumatic stress disorder (PTSD) is a common comorbidity of fibromyalgia. However, limited prospective data are available on the development of fibromyalgia after exposure to high‐magnitude stress.
Jay B. Higgs, Willie J. Hale, Casey L. Straud, Jim Mintz, Stacey Young‐McCaughan, Kimberly D. Gomes, Chelsea J. Sterne, Katrina M. Lawrence‐Wolff, Alan J. Bartholomew, Kevin M. Kelly, Douglas M. Maurer, Catherine Vriend, Brett T. Litz, Douglas E. Williamson, Alan L. Peterson, for the STRONG STAR Consortium   +15 more
wiley   +1 more source

Wounded Objects: Mexican and Global Contexts of Disposable Life

Performance Philosophy
This article proposes the concept of the wounded object as an approach to perceptions and representations of disability, wounding, and death, and in particular to ambivalent separations between the living and the dead, the human and the non-human, the ...
Susan Antebi
doaj   +1 more source

Wounding patterns and human performance in knife attacks: optimising the protection provided by knife-resistant body armour [PDF]

, 2003
Stab attacks generate high loads,1 and to defeat them, armour needs to be of a certain thickness and stiffness.2,3 Slash attacks produce much lower loads and armour designed to defeat them can be far lighter and more flexible.Methods and subjects: Phase
Bleetman, A, Champion, Stephen M., Horsfall, Ian, Watson, Celia H.   +3 more
core   +1 more source