Results 151 to 160 of about 814,933 (365)
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian +6 more
wiley +1 more source
Review of Centella asiatica (L.) Urban.
AB-Boshghabi (Centella asiatica) from Apiaceae family, has been used as a traditional herbal medicine in Asiatic countries for hundreds of years. This plant is indigenous to the warmer regions of both hemispheres, including southeast Africa, Asia ...
M Taghizadeh +3 more
doaj
Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu +12 more
wiley +1 more source
Case of Stab (Knife) Wound of the Abdomen with Prolapse and Lesion of the Small Bowel [PDF]
D Bekleinsheff
openalex +1 more source
Fear and Faith In the Fields of Our Hearts [PDF]
(Excerpt) In the name of the Father and of the Son and of the Holy Spirit. This morning\u27s sermon is in some ways a sermon that many of you have already preached this week.
Truemper, David G
core +1 more source
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li +5 more
wiley +1 more source

