Results 171 to 180 of about 316,219 (318)

Pressure Ulcers and Suprasorb X+PHMB Infection, prevention and treatment [PDF]

, 2010
Ousey, Karen
core  

Transient immunostimulation with LPS promotes tissue repair in aged skin. [PDF]

Immun Ageing
Haas P, Wang Y, Koroma AK, Cheng J, Aghapour M, Hainzl A, Krug L, Schatz S, Wlaschek M, Maity P, Scharffetter-Kochanek K, Singh K.   +11 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Clinical dosimetry and efficacy of LED photobiomodulation for chronic lower-limb wound healing: a systematic review of randomized trials. [PDF]

Lasers Med Sci
Miranda MB, Barros ACS, de Paula AVL, Alves RF, da Rocha RB, Cardoso VS.   +5 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Clinical severity-dependent virulence of <i>Staphylococcus aureus</i> from human diabetic foot ulcers drives impaired wound healing in a diabetic murine model. [PDF]

Front Cell Infect Microbiol
Seo KS, Nicols LM, Palmer CD, Hellmann KT, Robinson DA, Olivier AK, Thornton JA, Ferdous K, Brookshire WC, Park JY.   +9 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Reactive Nitrogen-Dominant Plasma Accelerates Diabetic Wound Healing Through Regulated Angiogenesis and TGF-β Normalisation. [PDF]

Int Wound J
Cheng YP, Chou-Huang TY, Lee CC, Chen HL, Cheng KY, Wu MC, Huang SS, Guo JW, Wu JS.   +8 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Prevalence of wounds and patient characteristics in an Australian community setting: a retrospective cohort study. [PDF]

BMJ Open
Purcell A, Brinton J, King J, Munford LA, Hibbard K, Cullum N.   +5 more
europepmc   +1 more source