Results 231 to 240 of about 814,933 (365)

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

12/15-lipoxygenase orchestrates murine wound healing via PPARγ-activating oxylipins acting holistically to dampen inflammation. [PDF]

Proc Natl Acad Sci U S A
Thomas CP, Tyrrell VJ, Burston JJ, Johnson SRC, Aldrovandi M, Alvarez-Jarreta J, Inglis R, Leonard A, Fice L, Costales J, Vidal-Puig A, Protty M, Guy C, Andrews R, Szomolay B, Cossins BC, Cardus Figueras A, Carobbio S, Jones SA, O'Donnell VB.   +19 more
europepmc   +1 more source

Chronic Pain in Parkinson’s Disease: Prevalence, Sex Differences, Regional Anatomy and Comorbidities

Annals of Clinical and Translational Neurology, EarlyView.
Chronic pain affected 66.2% of 10,631 individuals with Parkinson's disease, with higher prevalence and severity in females. Pain most often involved the buttocks, lower back, neck, and knees, and was linked to depression, sleep disorders, and osteoarthritis.
Natalia S. Ogonowski, Freddy Chafota, Fangyuan Cao, Amanda Wei Yin Lim, Victor Flores‐Ocampo, Santiago Díaz‐Torres, Zuriel Ceja, Luis M. García‐Marín, Scott F. Farrell, Kishore R. Kumar, Jane Alty, George D. Mellick, Trung Thành Ngô, Miguel E. Rentería   +13 more
wiley   +1 more source

Correction: Bovine Dermal Collagen Matrix Promotes Vascularized Tissue Generation Supporting Early Definitive Closure in Full-Thickness Wounds: A Pre-clinical Study. [PDF]

Cureus
Bush KA, Nsiah BA, Jay JW, Penny RA, Jahid S, Kashgari GY, Doshi NK, Valerio IL.   +7 more
europepmc   +1 more source

WOUNDING AND SUGAR TRANSLOCATION [PDF]

, 1945
F. W. Went, Marcella Carter
openalex   +1 more source

The Wound Dresser

Methodist DeBakey Cardiovascular Journal, 2022
openaire   +3 more sources

Genetic Modifiers of Parkinson's Disease: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the associations of LRRK2 p.G2019S, GBA1 p.N409S, polygenic risk scores (PRS), and APOE E4 on PD penetrance, risk, and symptoms. Methods We conducted a US‐based observational case–control study using data from the 23andMe Inc. and Fox Insight Genetic Substudy (FIGS) databases.
Matthew J. Kmiecik, Michael V. Holmes, Pierre Fontanillas, Giulietta M. Riboldi, Ruth B. Schneider, Jingchunzi Shi, Anna Guan, Susana Tat, Steven Micheletti, Keaton Stagaman, Josh Gottesman, David A. Hinds, Joyce Y. Tung, 23andMe Research Team, Stella Aslibekyan, Lucy Norcliffe‐Kaufmann   +15 more
wiley   +1 more source

Bioinspired wearable polymer microneedle patches: pioneering diabetic wound therapy for the horizon. [PDF]

RSC Adv
Zhang S, Wei M, Luan C, Gao B.
europepmc   +1 more source

SURGICAL MANAGEMENT OP GUNSHOT WOUNDS OF THE PELVIC VISCERA AND THEIR LATE COMPLICATIONS

, 1947
Geoege Benton Sanders, Ian G. Hodge
openalex   +2 more sources

ON THE SALT PACK TREATMENT OF INFECTED GUNSHOT WOUNDS [PDF]

, 1916
J. E. H. Roberts, Rachel Statham
openalex   +1 more source