Results 61 to 70 of about 992,812 (310)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

The feasibility of a social media-based foot self-management education and support program for adults with diabetes: A partially randomized preference trial

open access: yesPEC Innovation
Aim: To assess the feasibility of Diabetic Foot Care Group (DFCG), a social media-based self-management education and support intervention, for people with diabetes (PWD) empowerment in diabetes-related foot ulceration prevention.
Helen Ngozichukwuka Obilor   +6 more
doaj   +1 more source

Effects of Adipose-Derived Stem Cells and Their Conditioned Medium in a Human Ex Vivo Wound Model [PDF]

open access: gold, 2022
Xiao Guo   +4 more
openalex   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Inter‐device agreement of sacral subepidermal oedema measurement in healthy adults during prolonged 60° head of bed elevation

open access: yesNursing Open
Aim To investigate the level of agreement between the SEM 200 and Provisio® subepidermal moisture sacral delta measurements, which may indicate increased pressure injury risk, in healthy adults during 120 min of prolonged 60° head of bed elevation.
Sharon L. Latimer   +4 more
doaj   +1 more source

Management of patients with autoimmune liver diseases on the basis of the latest EASL recommendations and our own experience (lecture to a practical doctor)

open access: yesPatologìâ, 2018
Autoimmune hepatitis (AIH), primary biliary cirrhosis/cholangitis (PBC), primary sclerosing cholangitis (PSC) and autoimmune cholangiopaties are the autoimmune liver diseases.
Yu. M. Stepanov   +2 more
doaj   +1 more source

Calreticulin: a multifunctional protein with potential therapeutic applications for chronic wounds [PDF]

open access: gold, 2023
Andrew P. Sawaya   +7 more
openalex   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The financial burden of chronic wounds in primary care: A real-world data analysis on cost and prevalence

open access: yesInternational Journal of Nursing Studies Advances
Background: Chronic wounds place a substantial clinical and economic burden on health systems and significantly reduce the quality of life of those affected.
Miguel Ángel Díaz-Herrera   +11 more
doaj   +1 more source

Microneedle arrays for the treatment of chronic wounds

open access: yesExpert Opinion on Drug Delivery, 2020
Introduction Chronic wounds are seen frequently in diabetic and bedbound patients. Such skin injuries, which do not heal in a timely fashion, can lead to life-threatening conditions.
Lindsay Barnum   +3 more
semanticscholar   +1 more source

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