Results 81 to 90 of about 661,305 (314)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Marrow-derived stromal cell delivery on fibrin microbeads can correct radiation-induced wound-healing deficits. [PDF]
, 2013 Skin that is exposed to radiation has an impaired ability to heal wounds. This is especially true for whole-body irradiation, where even moderate nonlethal doses can result in wound-healing deficits.
Gaberman, Elena +6 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The evidence supporting the use of honey as a wound dressing [PDF]
, 2006 Some clinicians are under the impression that there is little or no evidence to support the use of honey as a wound dressing. This impression is reinforced by it being concluded in systematic reviews that the evidence is not of a high standard.
Molan, Peter C.
core +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Antimicrobial Peptides and Their Therapeutic Potential for Bacterial Skin Infections and Wounds
Frontiers in Pharmacology, 2018 Alarming data about increasing resistance to conventional antibiotics are reported, while at the same time the development of new antibiotics is stagnating.
Anja Pfalzgraff +2 more
doaj +1 more source
Resistance of Scotch Pine Varieties to Zimmerman Pine Moth (Lepidoptera: Pyralidae) and Its Impact on Sales in a Choose and Cut Christmas Tree Plantation [PDF]
, 2017 Nine varieties of Scotch pine, Pinus sylvestris, were assessed for their susceptibility to Zimmerman pine moth, Dioryctria zimmermani, in a choose and cut Christmas tree plantation.
Sadof, Clifford S
core +3 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Honey anti-inflammatory factor identified [PDF]
, 2012 Four different brands of honey wound dressings are now on sale internationally as registered medical devices, all made from manuka honey because of its well-established reputation as an antibacterial agent.
Molan, Peter C.
core +1 more source