Results 91 to 100 of about 661,305 (314)

Bacterial Growth Kinetics under a Novel Flexible Methacrylate Dressing Serving as a Drug Delivery Vehicle for Antiseptics [PDF]

, 2013
A flexible methacrylate powder dressing (Altrazeal®) transforms into a wound contour conforming matrix once in contact with wound exudate. We hypothesised that it may also serve as a drug delivery vehicle for antiseptics.
Archibald, Assadian, Axel Kramer, Beldon, Braga, Chen, Christina Forstner, Clark, Cutting, David Leaper, Deitch, Disemond, Eberlein, Fang, Fitzgerald, Henry-Stanley, Hirsch, Johannes Leitgeb, Keith Cutting, Kim, Lalani, Leaper, Leaper, Migliaresi, Minnich, Nathan, Nordmann, Ojan Assadian, Rupert Schuster, Sibbald, Tsou, Vanscheidt, Verena Dosch, Wang, Winter   +34 more
core   +4 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

No drain, autologous transfusion drain or suction drain? A randomised prospective study in total hip replacement surgery of 168 patients [PDF]

, 2010
We performed a prospective, randomised controlled trial to assess the differences in the use of a conventional suction drain, an Autologous Blood Transfusion (ABT) drain and no drain, in 168 patients.
Alcock, RJ, Bing, AJ, Carmont, MR, Cheung, G, Graham, NM, Kuiper, JH   +5 more
core  

The Debrisoft ® monofilament debridement pad for use in acute or chronic wounds: A NICE medical technology guidance [PDF]

, 2015
As part of its Medical Technology Evaluation Programme, the National Institute for Health and Care Excellence (NICE) invited a manufacturer to provide clinical and economic evidence for the evaluation of the Debrisoft ® monofilament debridement pad for ...
A Piaggesi, AW Goode, B Campbell, Catherine Meads, D Gray, D Williams, Eleonora Lovato, F Smith, I Michiels, J Edwards, J Stephen-Haynes, J White, JC Dumville, JC Dumville, JFP Posnett, JL Jensen, K Withers, Louise Longworth, M Bradley, M Doerler, MO Soares, P Raynor, PA D’Hemecourt, R Strohal, RG Brunner, S Bahr, S Johnson   +26 more
core   +2 more sources

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Modelling strategies for the healing of burn wounds [PDF]

, 2007
Epidermal wound healing requires the coordinated involvement of complex cellular and biochemical processes. In the case of epidermal wounds associated with burns, the healing process may be less than optimal and may take a significant amount of time ...
Denman, Paula Kerri
core   +1 more source

Penetrating injuries in dogs and cats: a study of 16 cases [PDF]

, 2008
The objective of this retrospective study was to assess radiographical and surgical findings, surgical management and outcome of penetrating injuries in dogs and cats by evaluating patient records.
De Rooster, Hilde, Risselada, M, Taeymans, O, van Bree, Henri   +3 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Tight Swimming Trunks to Prevent Post Scrotal Surgery Hematoma An Experimental Justification

Urology Journal, 2013
Purpose: To conduct a study to measure the pressure effects of the different scrotal supports appliedon a simulated expanding scrotal hematoma.Materials and Methods: We created a model of an expanding hematoma with simultaneous pressurerecording using a ...
Yahya A Al-Abed, Thomas W Carr
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