Results 111 to 120 of about 316,219 (318)

Diabetic foot ulceration with osteomyelitis: the importance of early detection [PDF]

open access: yes, 2008
This case study explores the management of a chronic diabetic foot ulcer complicated by severe soft tissue infection (cellulitis) and bony infection (osteomyelitis) in a patient with type 2 ...
Tranter, Jennifer, McIntosh, Caroline
core  

Bio-Conjugated Polycaprolactone Membranes: A Novel Wound Dressing

open access: yesArchives of Plastic Surgery, 2014
Background The combination of polycaprolactone and hyaluronic acid creates an ideal environment for wound healing. Hyaluronic acid maintains a moist wound environment and accelerates the in-growth of granulation tissue.
Elijah Zhengyang Cai   +13 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

An Overview of Wound Dressing Materials

open access: yesPharmaceuticals
Wounds are an increasing global concern, mainly due to a sedentary lifestyle, frequently associated with the occidental way of life. The current prevalence of obesity in Western societies, leading to an increase in type II diabetes, and an elderly ...
Tânia Lagoa   +2 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Developing a real time sensing system to monitor bacteria in wound dressings [PDF]

open access: yes, 2012
Infection control is a key aspect of wound management strategies. Infection results in chemical imbalances and inflammation in the wound and may lead to prolonged healing times and degradation of the wound surface.
Iain S. Hunter   +5 more
core   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

The Effect of a Myostatin Antagonist on the Healing of Burn Wounds in Skin. [PDF]

open access: yes, 2009
The body's remarkable ability to repair itself from damage is both very useful and extremely complex. The wound healing system is characterised by four overlapping phases: hemostasis, inflammation, proliferation, and remodelling.
Fieten, Daniel John
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Defining, assessing and managing cavity wounds [PDF]

open access: yes, 2016
NoThis paper provides an overview of cavity wounds, focusing on the definition, assessment and management of a common clinical problem in wound care.
Vowden, Kath
core  

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