Results 121 to 130 of about 316,219 (318)
Vacuum assisted closure technique: a short review
The Pan African Medical Journal, 2017 The management of difficult to heal wounds has always been a cause of concern for the treating clinicians. There has been a tremendous increase in the number patients presenting with difficult to heal wounds.
Sankalp Yadav, Gautam Rawal, Mudit Baxi
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Wounds UK debate: Dressing choice - What's the X-Factor? [PDF]
, 2012 n November 2011, the Wounds UK Harrogate conference hosted the inaugural Wounds UK debate, which focused on the subject of dressings and how exactly clinicians are supposed to make the right choices for patients, especially when confronted with the ...
Roberts, Carol +5 more
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Using honey in wound care [PDF]
, 2006 Honey is primarily a herbal product with some modifications that are made by the bees that process the nectar or sap collected from the plants to store as honey. The types of phytochemicals present in a honey depend on the plant source of the honey.
Molan, Peter C., P. C. Molan
core
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Lifestyles of bacteria in wounds: Presence of biofilms? [PDF]
, 2001 Biofilms consist of bacteria and other organisms that live within a matrix of extracellular polysaccharide (EPS) and have been implicated in bacterial diseases, such as otitis media, dental plaque, and chronic infections in cystic fibrosis.
Davis, S C +4 more
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Sharing best practice at Wounds UK Harrogate 2012 [PDF]
, 2012 Welcome to the 2012 Wounds UK conference issue. When we reflect on the last 12 months, we have seen an abundance of media stories surrounding poor practice in healthcare, including patients left on trolleys for long periods of time, patients not ...
Fletcher, Jacqui, Ousey, Karen
core