Results 121 to 130 of about 1,971,412 (267)

Why do older people not adhere to a healthy lifestyle: a qualitative exploration of perceived barriers among older people living in a low-income and middle-income country setting

open access: yesBMJ Open
Objective To explore perceived barriers to adhering to a healthy lifestyle among older people living in a Sri Lankan setting.Design Qualitative thematic analysis of in-depth interviews among older people.Setting The study was conducted in Kalutara ...
Chrishantha Abeysena   +2 more
doaj   +1 more source

Weierstrass $\wp$-function [PDF]

open access: yesApplications of Mathematics, 1971
openaire   +1 more source

Promoter Hypermethylation‐Induced Silencing of FXYD1 Drives Breast Cancer Metastasis via DDX5‐Mediated Wnt/β‐Catenin Pathway Activation

open access: yesAdvanced Science, EarlyView.
This study identifies FXYD1 as an epigenetically silenced tumor suppressor in breast cancer. DNA methylation turns off the gene FXYD1 in breast cancer, and low levels predict worse outcomes. Restoring FXYD1 limits breast cancer cells proliferation and metastasis. In the nucleus, FXYD1 recruits the E3 ligase MAEA to K63‐ubiquitinate DDX5 for proteasomal
Ping Wen   +11 more
wiley   +1 more source

The Enhanced Whey Protein Oral Bioavailability and Muscle Anabolism Ability by a Simple and Effective Piperine‐Whey Protein Synergistic Codelivery System

open access: yesAdvanced Science, EarlyView.
WP(Pip) is a mixture of whey protein and piperine‐loaded nanoemulsion stabilized by WP through microfluidic homogenization. Acting as a “smart key,” piperine opens epithelial tight junctions to enhance absorption of whey protein and, thereby increasing circulating amino acid availability, synergistically up‐regulates the mTOR signaling pathway in ...
Qing Yue   +10 more
wiley   +1 more source

FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li   +16 more
wiley   +1 more source

Past Fire and Vegetation Change in the Hyperdiverse Forests of the Ecuadorian Amazon

open access: yesPlants
The Ecuadorian Amazon holds more biodiversity than most other places on Earth. Palms are a particularly dominant component of the vegetation; however, it remains unknown to what degree the pattern has persisted through time.
Britte M. Heijink   +12 more
doaj   +1 more source

Sub‐Unit‐Cell Logic Governs Transport in TPMS Architectures

open access: yesAdvanced Science, EarlyView.
ABSTRACT Next‐generation energy, thermal, and chemical systems require architectures capable of highly efficient transport across multiple length scales. Triply periodic minimal surfaces (TPMS), first conceptualized in 1865, offer inherently scalable geometries with exceptional transport potential, yet mechanistic links between topology and performance
Haozhang Zhong   +16 more
wiley   +1 more source

Relationship between body dimensions and the diameter of a 4‐strand ACLR graft

open access: yesJournal of Experimental Orthopaedics
Purpose The objective of this study is to create a probability table outlining the chance of preparing a ‘doubled semitendinosus and doubled gracilis’ (ST×2 + G×2) graft for anterior cruciate ligament reconstruction (ACLR) with minimum diameters of 7 and
WP Yau
doaj   +1 more source

A Soft Matrix Microenvironment Promotes Laterally Spreading Tumors via Oxidative Phosphorylation‐Dependent Cell Adhesion

open access: yesAdvanced Science, EarlyView.
Laterally spreading tumors (LSTs) are precancerous colorectal lesions characterized by a flat morphology. This study reveals a mechanochemical pathway through which a soft matrix microenvironment diminishes spatial constraints in intestinal adenomas. This process promotes deficiencies in tight junction proteins, mediated by the mechanoreceptor ADORA2B ...
Jiamin Zhong   +21 more
wiley   +1 more source

Predictions of Individual Differences in the Acquisition of Native and Non-Native Languages: An Update of BLC Theory

open access: yesLanguages
BLC Theory proposes that individual differences (IDs) in language proficiency (in both native and non-native speakers) can poorly be mapped on a single proficiency scale.
Jan Hulstijn
doaj   +1 more source

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