Results 111 to 120 of about 434,135 (308)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Gender inequality in the Nordic film industry: Exploring above-the-line positions in film production

open access: yesNordic Journal of Media Studies
In this article, we explore the enduring barriers to gender equality in the Nordic film industry, with a focus on positions of power and structural biases.
Loist Skadi   +3 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Federal Writers Project historical records survey bulletin board photograph

open access: yes, 1930
Dated to the 1930s or 1940s, this photograph shows a bulletin board displaying pamphlets and articles produced by writers of the Federal Writers Project in Ohio. This is one of the many visual materials collected for use in the Ohio Guide.
Ohio Federal Writers' Project
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Portuguese writers and scientists exiled in Brazil

open access: yesVibrant: Virtual Brazilian Anthropology, 2014
This article analyses the relationship and tensions between cosmopolitan­ism and particularism in the way in which the subject of exile is broached in the life stories, works and ideas of the Portuguese writers Adolfo Casais Monteiro, Jorge de Sena and ...
Douglas Mansur da Silva
doaj  

Federal Writers Project at the Ohio State Fair

open access: yes, 1935
Reverse reads: "State Fair 1937" The Federal Writers' Project (FWP) was a United States federal government project to fund written work and support writers during the Great Depression.
Ohio Federal Writers' Project
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Investigating the writing strategies of fourth year Libyan university students of English: strategy differences between good and poor writers of English [PDF]

open access: yes, 2014
The present study is an investigation of the composing processes and writing strategies of fourth year Libyan university students majoring in English as a foreign language. The study predominantly adopts a qualitative approach, using a number of research
Elshawish, MF
core  

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