Results 121 to 130 of about 434,135 (308)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Writers Talk Featuring Dan Gediman Fathers Day Special
, 2011 In conjunction with its interview of Dan Gediman, editor of THIS I BELIEVE: On Fatherhood, Writers Talk produced a special Father's Day broad/podcast featuring essays by OSU student, staff, and faculty writers.The media can be accessed here: http ...
Gediman, Dan
core +1 more source
Asedios a la forma: teorías (clásicas y nuevas) del cuento
Perífrasis. Revista de Literatura, Teoría y Crítica, 2014 La Edad de Oro del cuento latinoamericano tuvo lugar entre 1945 y 1965 con la publicación de libros que revolucionaron el género. En ese mismo período ocurría un proceso más secreto: las reflexiones sobre el cuento.
Pablo Brescia
doaj
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Writers Talk 3rd Annual Halloween Special
, 2011 The third annual Writers Talk Halloween special, featuring the short story "Hello, Slocum," written by OSU creative writing alumnus Juliet Williams and performed by Fort Hayes theatre students.
8th Floor Improv +2 more
core +1 more source
Вестник Кемеровского государственного университета, 2014 The paper is devoted to formation and development of Kemerovo branch of the Union of Writers of the Russian Soviet Federative Socialist Republic, which was created in 1962.
A. M. Sherin
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source