Once upon a time in the anthropocene: myths, legends, and futurity in Turkish climate fiction. [PDF]
Middle East Lit, 2023 Tabur M.
europepmc +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Enough Suffering: Thoughts on Suffering and Virtue. [PDF]
J Value Inq, 2021 Coplan A, Battaly H.
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
"Worlds. . .[of] Contingent Possibilities": Genderqueer and Trans Adolescents Reading Fan Fiction. [PDF]
Telev New Media, 2022 Duggan J.
europepmc +1 more source
Popculture in postcolonial literature Motifs of popular culture in Arundhati Roy’s The God of Small Things and Eden Robinson’s Monkey Beach [PDF]
, 2015 Mrak, Anja
core +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Reimagining Identity in Postcolonial East African Literature: A Comparative Analysis of Ngugi wa Thiong'o and Abdulrazak Gurnah. [PDF]
F1000ResJani BJ.
europepmc +1 more source
On not being able to read: doomscrolling and anxiety in pandemic times. [PDF]
Textual Pract, 2023 Salisbury L.
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source