Results 61 to 70 of about 65,383 (222)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Drawing Elena Ferrante's Profile. Workshop Proceedings, Padova, 7 September 2017 [PDF]
, 2018 Elena Ferrante is an internationally acclaimed Italian novelist whose real identity has been kept secret by E/O publishing house for more than 25 years.
Arjuna Tuzzi, Michele A. Cortelazzo
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Creolization and the collective unconscious: locating the originality of art in Wilson Harris' Jonestown, The Mask of the Beggar and The Ghost of Memory [PDF]
, 2008 Alongside the essays and fiction of Edouard Glissant, Wilson Harris's writings stand as one of the most important contributions to Caribbean creolization theory.
Burns, L.
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
"Familiar Artifice": Ways of Telling in the Short Story, Psychoanalysis, and Alice Munro's "The Moons of Jupiter". [PDF]
J Am Psychoanal Assoc, 2022 Rizq R.
europepmc +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Incorporating Local Wisdom Into Creative Writing: Exploring the Students Perception Towards the Significance of Cultural Identity [PDF]
, 2016 Telah banyak penelitian yang menunjukkan bahwa nilai-nilai kearifan lokal, secara umum, telah banyak bergeser dan bahkan cenderung tergerus. Dalam banyak hal, globalisasi menggeser persepsi para agen budaya masa kini atas pentingnya warisan nilai-nilai ...
Herminingrum, S. (Sri) +1 more
core +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source