Results 71 to 80 of about 65,383 (222)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

The Return of the Poor Man: Jude the Obscure and Late Victorian Socialism

open access: yes, 2016
This essay examines Hardy\u27s decision at the end of his career as a novelist to return to the striking socialistic themes which had defined his first (unpublished) novel.
Flynn, Suzanne J.
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Neurodiversity, Networks, and Narratives: Exploring Intimacy and Expressive Freedom in the Time of Covid-19. [PDF]

open access: yesSoc Incl, 2023
Betts K   +12 more
europepmc   +1 more source

The migrant voice : the politics of writing home between the Sinophone and Anglophone worlds

open access: yes, 2017
This paper addresses the politics of language, identity, and diasporic Chinese writing in old and emerging Chinese migrant literature. I opt for the idea of a “migrant subject” as brought up by Ha Jin to underscore a diverse verbal strategy and mobile ...
NG, Kenny K. K.
core  

Trends in contemporary Italian narrative 1980-2007 [PDF]

open access: yes, 2007
The ‘new Italian narrative’ that began to be spoken about in the 1980s was not associated with a single writer or movement but with an eclectic and varied production.
Ania, GF, Hallamore-Caesar, A
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Literature in Estonia [PDF]

open access: yes, 1943
http://www.ester.ee/record=b1203590 ...
Harris, Ernest Howard
core  

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