Results 161 to 170 of about 4,527,470 (293)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Genetic Testing Station Provides Increased Access to Germline Genetic Testing for Pediatric Oncology Patients. [PDF]

J Genet Couns
Hamilton C, Duan E, Niell-Swiller M, Bhansali F, Hoover A, Bottomley S, Dorrani N, Palmer C, Lewis M, Woo K, Russell B, Martinez-Agosto JA, Karlan B, Federman N, Chang VY.   +14 more
europepmc   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Adult choledochal cyst resection in Scandinavia: uncommon malignancy and considerable morbidity in a multicentre surgical cohort. [PDF]

BJS Open
Busund S, Engstrand J, Taflin H, Tingstedt B, Lundgren L, Urdzik J, Gkekas I, Sparrelid E, Yaqub S, Sturesson C.   +9 more
europepmc   +1 more source

Write less, write well [PDF]

Cortex, 2015
Cubelli, Roberto, Della Sala, Sergio
openaire   +4 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Metamodernism: Historicity, Affect, and Depth After Postmodernism (Eds.) Robin van den Akker, Alison Gibbons, and Timotheus Vermeulen

C21 Literature: Journal of 21st-century Writings, 2020
Zebadiah Robert Kraft
doaj   +2 more sources

A Rare Hepatoblastoma in a 10-Year-Old Boy Presenting With Tumor Rupture and Normal Alpha-Fetoprotein Levels: A Case Report. [PDF]

Clin Case Rep
Paul CH, Swallow A, Shedura VJ, Lazaro A, Kitua D, Philipo A, Katwana D, Jackson AK, Haule G, Gaskill C, Kahindi KB, Balowa M, Massawe G, Mwanga A.   +13 more
europepmc   +1 more source

History of Black Writing (HBW) Blog, 2011-2021

Guest contributors to the History of Black Writing Blog included leading scholars and writers, but the majority of the posts were conceived of, researched, and written by undergraduate and graduate students.
Project on the History of Black Writing
core  

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source