Results 181 to 190 of about 3,173,843 (314)
Only One Percent of Important Shark and Ray Areas in the Western Indian Ocean Are Fully Protected From Fishing Pressure. [PDF]
Ecol EvolCochran JEM, Charles R, Temple AJ, Kyne PM, García-Rodríguez E, Gonzalez-Pestana A, Batlle-Morera A, Mouton TL, Armstrong AO, Rohner CA, Coker DJ, Hardenstine RS, Kattan A, McIvor AJ, Peinemann VN, O'Toole KA, Palm L, Richardson EB, Akhilesh KV, Ali Abedi H, Almealla RK, Almojil D, Andrzejaczek S, Askin AN, Banerjee AA, Bargahi HR, Barnes AJ, Barteneva-Vitry S, Behzadi S, Bein A, Bennett RH, Bocchi F, Boldrocchi G, Braulik GT, Braun CD, Brighton E, Budd FKP, Bullock RW, Canovas Perez C, Carlisle AB, Carpenter M, Chapple TK, Chaúca I, Cliff G, Crochelet E, Cullain N, Curnick DJ, Daly R, de Necker L, Diamant S, Donati GFA, Ebert DA, Eid E, Elhassa IS, Elston C, Everett BI, Farrag MMS, Fassbender N, Fennessy ST, Fernando SMC, Finucci B, Flam AL, Gausman P, Gauthier ARG, Sreekanth GB, Gupta T, Hafeez M, Hagy BN, Haines JLA, Harris JL, Harvey-Carroll J, Hempson TN, Hilbourne ST, Hsu HH, Ibrahim ND, Jacoby DMP, Jaquemet S, Babu K K I, Karnad D, Kaunda-Arara B, Kizhakudan SJ, Kock AA, Koester A, Kuboja BN, Kuguru BL, Lea JSE, Mahadalle O, Manjebrayakath H, Mason-Parker C, Mateos-Molina D, Menon M, Moore ABM, Mourier J, Murra TS, Nakhawa AD, Nazurally N, Nelso LE, Nevill JEG, Olbers JM, Ostrovski RL, Peel LR, Perisic N, Peterson B, Pierce SJ, Pittman SJ, Rahangdale S, Rambahiniarison J, Rastgoo AR, Rezaie-Atagholipour M, Robinson DP, Samoilys MA, Sawers TJ, Scannell BJ, Schmidt JV, Silva IM, Silva L, Solonomenjanahary J, Spaet JLY, Stevens GMW, Strike EM, Thomas S, van Beuningen D, Venables SK, Vossgaetter L, Weideli OC, Williams ID, Williams CT, Willson AJ, Wilson L, Zareer IH, Zerr KM, Berumen ML, Jabado RW. +132 moreeuropepmc +1 more sourceWriting Life, Writing Time, Writing the Mother
Age, Culture, HumanitiesThis article focuses on Ernaux’s later life memories of a twentieth century daughter-mother relationship, rendered in the light of this era’s historical transformations and its tensions between individual freedom and collective ‘fate’, and between pre- and post 1968 conceptions of a fulfilled life.openaire +1 more sourceAdaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch +16 morewiley +1 more sourcePatient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert +16 morewiley +1 more sourceExploring the physiological limits of aging: a case study of the male 50-km world record in the 80+ age category. [PDF]
Front PhysiolPilotto AM, Higueras-Liébana E, Ansaldo M, Baltasar-Fernandez I, Neri M, Giusti L, Buendía-Romero Á, Valenzuela PL, Alcazar J, Lauretani F, Re R, Botter A, Franchi MV, Ara I, Porcelli S. +14 moreeuropepmc +1 more source