Results 241 to 250 of about 3,006,902 (314)

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

Molecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla, Jana R. Crespo, Saioa Garcia‐Longarte, Marta Fidalgo, Sara del Palacio, Natalia Martin‐Martin, Onintza Carlevaris, Ianire Astobiza, Sonia Fernández‐Ruiz, Marc Guiu, Laura Bárcena, Isabel Mendizabal, Ana M. Aransay, Mariona Graupera, Roger R. Gomis, Arkaitz Carracedo   +15 more
wiley   +1 more source

Identifying and mitigating the biological effectors of the social determinants of health in cancer. [PDF]

J Natl Cancer Inst
Wagner M, Benson CL, Obeng-Gyasi S, Conzen S, Mccullough LE, Halbert CH, Gerson SL.   +6 more
europepmc   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Yes, Bridges Do Connect!-A Rare Case of Coronary Sinus Communicating Into the Left Atrium Through a Bridging Vein. [PDF]

Clin Case Rep
Aryal M, Neupane NP, Rajlawot K, Paudel I, Koirala S, Keshari S, Pandey A.   +6 more
europepmc   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Independent confirmation of the immunophenotypic ELN Scoring System in patients with MDS and CMML. [PDF]

Hemasphere
Oelschlaegel U, Schadt J, Epp K, Wagenführ L, Ruhnke L, Kroschinsky F, Bornhäuser M, Sockel K, von Bonin M, Röhnert MA.   +9 more
europepmc   +1 more source

The First Report on Cat Flea (Ctenocephalides felis), a Zoonotic Haematophagous Insect Infestation in Humans in Bangladesh: A Case Report and Literature Review. [PDF]

Vet Med Sci
Shohana NN, Hossain MS, Labony SS, Ali MH, Alim MA, Nandi AK, Anisuzzaman.   +6 more
europepmc   +1 more source

Adult-Onset Partial Unilateral Lentiginosis: A Rare Pigmentary Mosaicism With Clinical Response to Tranexamic Acid. [PDF]

Clin Case Rep
Pudasaini N, Poudel S, Pokharel A, Mishra A, Dangol AKS, Chapagain M.   +5 more
europepmc   +1 more source

Writing The Writing on the Wall

London Review of International Law, 2018
openaire   +2 more sources