Results 91 to 100 of about 529,568 (297)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Reading comprehension in developmental disorders of language and communication [PDF]

open access: yes, 2011
Background:  Deficits in reading airment (SLI), Down syndrome (DS) and autism spectrum disorders (ASD). Methods:  In this review (based on a search of the ISI Web of Knowledge database to 2011), the Simple View of Reading is used as a framework for ...
Ricketts, Jessie, Jessie Ricketts
core   +1 more source

The Difference of Oral Reading and Writing of Tiociu Languag

open access: yesLingua Cultura, 2013
Article presented the difference of oral reading and writing of TioCiu Guangdong Language, Tiongkok. The language is divided by its oral and writing regulation consisting of three factors: consonant, vocal, and tone, as well as the description of ...
Lily Thamrin
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

The reactivity of think-alouds in writing research: Quantitative and qualitative evidence from writing in English as a foreign language

open access: yes, 2019
The reactivity of think-alouds (TAs) (i.e., their effects on thinking) has remained an inevitable concern whenever their use is considered or evaluated. This paper reports findings from a study that involved 85 Chinese sophomores, who, having received some
Yang, C, Parr, Judith, Zhang, LJ
core   +1 more source

Writing and reading queerly: Foucault’s aesthetics of existence and queer self-making [PDF]

open access: yes, 2015
Michel Foucault advocated an ongoing assembly and disassembly of subjectivity that constituted a kind of self-bricolage; a making and re-making of subjectivity that he saw as an aesthetic struggle towards an artistic ideal.
Baker, Dallas J.
core   +1 more source

Concurrent Reading While Writing

open access: yesACM Transactions on Programming Languages and Systems, 1983
The problem of asynchronous processes reading shared data while the data are being modified by another process is considered. This problem differs from the standard readers/writers problem in that concurrent reading while writing is allowed. The model used here strongly limits the use and size of the shared variables.
openaire   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Morphological Correspondences in the Reading-Writing Relation among L2 Learners [PDF]

open access: yes, 2015
Studies show that morphological and lexical awareness is a particularly important variable for reading comprehension after the primary school years. Research on L1 students’ reading and writing competence has revealed correlations between reading and ...
Tonne, Ingebjørg, Pihl, Joron
core  

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