Results 131 to 140 of about 529,568 (297)

Examining the developmental trend of reading fluency in Chinese children’s reading comprehension in a one-year longitudinal study

open access: yes, 2022
Prior research on alphabetic readers has suggested that reading fluency plays an additional role in children’s development of reading comprehension. Yet, it is unclear whether this relationship can be extended to languages with non-alphabetic writing ...
Hsu, SJL, Ho, CSH
core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Literacy, multiliteracies and the teaching of reading and writing

open access: yes, 2017
In this chapter we will: - discuss contemporary theories and definitions of literacy and multi-literacies and how they relate to middle years students - examine literacy practices of, and for, diverse middle years students - present some useful models ...
Barton, Georgina, Lennon, Sherilyn
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Reading East Asian Writing The Limits of Literary Theory

open access: yes
This book presents contributions by thirteen scholars of Chinese and Japanese literature whose work is characterised by a strong interest in literary theory.
Smits, Ivo., Hockx, Michel.
core  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Reading, writing, rebelling. Propositions for a renewed critical stance

open access: yes, 2017
What is reading? What is writing? What connects the two? These questions have been the fertile ground for many literary and philosophical theories, from New Criticism to Deconstruction.
Sébastien Doubinsky
core  

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